University of California San Francisco

Jennifer Lai - 144
Jennifer
Lai
MD, MBA

Associate Professor of Medicine
General Hepatology and Liver Transplantation
Department of Medicine

Address

513 Parnassus Ave, MSB, #775A
San Francisco, CA 94117
United States

Email: [email protected]
Phone: 415-476-6422

ORCID: 0000-0003-2092-6380

Biography

Dr. Lai is a practicing general/transplant hepatologist and board-certified Physician Nutrition Specialist who specializes in caring for patients across the entire spectrum of liver disease, from diagnosis to liver transplant.

Dr. Lai is also a clinical investigator with a robust research program dedicated to improving the lives of patients living with chronic liver disease and to help more of them survive to transplant and thrive after. Her research program has been continuously supported by numerous organizations including the National Institutes of Health, American Association for the Study of Liver Diseases (AASLD), American Gastroenterological Association (AGA), American College of Gastroenterology (ACG), American Society of Transplantation (AST), and American Federation for Aging Research (AFAR), in addition to the generous support of grateful patients. She serves as director of the UCSF Health Advancing Research in Clinical Hepatology (ARCH), the research arm of the UCSF Division of GI/Hepatology, as well as director of Patient-Facing Research Core of the NIH-funded UCSF Liver Center.

Dr. Lai earned her B.S. from Stanford University and combined MD/MBA degrees from Tufts University School of Medicine, then completed her clinical training in Internal Medicine at Columbia University, and gastroenterology and advanced/transplant hepatology fellowships at UCSF. Dr. Lai has received many honors for her work including the SF Business Times Top 40 under 40 Leader award, AGA Young Investigator Award in Clinical Science, AST Clinical Science Career Development Award, Young Investigator Award from the International Liver Transplantation Society, and the UCSF Department of Medicine Resident Research Award. Currently, Dr. Lai serves as an Associate Editor for the Hepatology Journal (the premier hepatology journal) and a standing member of the U.S. FDA Gastrointestinal Drug Advisory Committee.

If you are interested in contributing to Dr. Lai's research program, please consider making a tax-deductible contribution: https://makeagift.ucsf.edu/LaiResearchFund

Awards & Honors

Award Conferred By Date
Distinction in Mentoring (UCSF Academic Senate) UCSF 2023
Long-Term Mentor Award UCSF Medical School 2021
Young Investigator Award in Clinical Science American Gastroenterological Association (AGA) 2020
Floyd Rector Internal Medicine Research Mentoring Award UCSF 2019
Fellow American Society of Transplantation 2017
AST/Novartis Faculty Development Award (grant) American Society of Transplantation 2016
Clinical Science Career Development Award American Society of Transplantation 2016
New Investigator Award American Geriatrics Society 2015
Young Investigator Award International Liver Transplantation Society 2015
Top 40 under 40 San Francisco Business Times 2015
Paul B. Beeson Scholar in Aging Research (grant) American Federation for Aging Research 2014
Associate Scholar Genius Award (grant) UCSF Pepper Center 2014
T. Franklin Williams Scholar (grant) Association of Specialty Professors 2013
Junior Faculty Career Development Award (grant) American College of Gastroenterology 2012
Transplant Hepatology Fellowship (grant) American Association for the Study of Liver Diseases 2011
Clinical Research Award (grant) American College of Gastrenterology 2011
Vanguard Award International Liver Transplantation Society 2011
Sylvia Allison Kaplan Clinical Research Award Northern California Kaiser Permanente 2009
Alpha Omega Alpha Tufts University School of Medicine 2005

Education

Institution Degree Dept or School End Date
UCSF Diversity, Equity, and Inclusion Champion 2021
Columbia University Medical Center Internship/Residency Internal Medicine
Stanford University B.S.
Tufts University School of Medicine M.D./M.B.A. Medicine / Healthcare administration
UCSF Advanced Training in Clinical Research
UCSF Fellowship in Advanced/Transplant Hepatology
UCSF Fellowship in Gastroenterology
University of Louisville Physician nutrition fellowship

Board Certifications

American Board of Internal Medicine
American Board of Internal Medicine - Gastroenterology

Collaboration Interests

I am interested in:

  • physician scientist

Clinical Expertise

Alcoholic Liver Disease

Autoimmune Hepatitis

Cirrhosis

Drug-Induced Hepatitis

Fulminant Hepatic Failure

Hemochromatosis

Hepatitis B

Hepatitis C

Hepatocellular Carcinoma (Liver Cancer)

Liver Transplantation

Living Donor Liver Transplantation

Nonalcoholic Fatty Liver Disease

Polycystic Liver Disease

Primary Biliary Cirrhosis

Primary Sclerosing Cholangitis

Program Affiliations

UCSF Liver Center

In the News

Dr. Jennifer Lai Honored for Research in Cirrhotic and Liver Transplant Patients
March, 20, 2015 | UCSF Transplant Surgery
Most Liver Transplant Candidates Receive Donation Offers
October, 22, 2014 | UCSF Transplant Surgery

Grants and Funding

  • The spectrum of cognitive impairment including Alzheimer’s Disease and related dementias after liver transplantation | NIH/NIA | 2023-09-15 - 2028-08-31 | Role: PI
  • Investigating the role of frailty on outcomes in acutely ill patients with cirrhosis undergoing liver transplantation in the acute care setting | NIH/NIDDK | 2023-07-15 - 2028-06-30 | Role: PI
  • The Impact of Frailty on Liver Transplant Outcomes in Older Adults with Hepatocellular Carcinoma | NIH/NIA | 2023-01-15 - 2027-12-31 | Role: PI
  • Predicting post-transplant mortality and global functional health based on pre-transplant functional status in liver transplantation | NIH | 2018-06-15 - 2023-05-31 | Role: PI
  • UCSF Liver Center | NIH | 1985-07-01 - 2023-05-31 | Role: Co-Investigator
  • Development of a laboratory frailty index to improve prediction of mortality in patients with cirrhosis awaiting liver transplantation | NIH | 2020-05-01 - 2022-04-30 | Role: Principal Investigator
  • Frailty and Functional Status in Older Liver Transplant Patients | NIH | 2014-09-15 - 2019-08-31 | Role: Principal Investigator
  • Global Functional Status in the Older Liver Transplant Candidate | NIH | 2013-08-15 - 2015-07-31 | Role: Principal Investigator

Research Narrative

Dr. Lai has engaged in research investigating clinical outcomes in patients with chronic liver disease. Her research focuses on three main areas:

1) Understanding the impact of functional status and physiologic reserve (i.e., frailty) in patients with cirrhosis awaiting liver transplantation (actively enrolling)

2) Evaluating the association between chronic hepatitis C and systemic inflammation with Vitamin D status and bone mineral density (actively enrolling)

3) Characterizing patterns of liver allocation and distribution and their association with liver transplant outcomes (both pre- and post-transplant) on a national level

Research Interests

Impact of function status in patients on the liver-transplant waiting list

Hepatitis C virus (HCV)

Patterns of donor liver allocation and liver transplant outcomes

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 305
  1. Material economic hardship is associated with adverse 1-year outcomes after pediatric liver transplantation: Prospective cohort results from the multi-center SOCIAL-Tx study.
    Wadhwani SI, Squires JE, Hsu E, Gupta N, Campbell K, Zielsdorf S, Vittorio J, Desai DM, Ebel NH, Shui AM, Bucuvalas JC, Gottlieb LM, Lyles CR, Lai JC, Society of Pediatric Liver Transplantation| | PubMed
  2. Pain in chronic liver disease compared to other chronic conditions: Results from a contemporary nationally representative cohort study.
    Zhang GY, Cortella A, Lai JC, Rubin JB| | PubMed
  3. Sex differences in patient-reported outcomes and perception of ascites burden amongst outpatients with decompensated cirrhosis and ascites.: Sex Differences in Ascites Burden Perception.
    Wong F, Reddy KR, Tandon P, Lai JC, Garcia-Tsao G, O'Leary JG, Biggins SW, Vagas HE, Thacker L, Kamath PS, Bajaj JS, NACSELD III Study Group| | PubMed
  4. Prognostic Communication, Symptom Burden, Psychological Distress, and Quality of Life Among Patients with Decompensated Cirrhosis.
    Donlan J, Kaplan A, Noll A, Pintro K, Horick N, Zeng C, Edelen M, Soetan Z, Comrie C, Indriolo T, Li L, Zhu E, Armstrong ME, Thompson LL, Zhou J, Diop MS, Mason N, Engel KG, Rowland M, Kenimer S, O'Brien K, Lai JC, Jackson V, Chung RT, El-Jawahri A, Ufere NN| | PubMed
  5. Clinical Sentiment Analysis by Large Language Models Enhances the Prediction of Hepatorenal Syndrome in Decompensated Cirrhosis.
    Lai M, Fenton C, Rubin J, Huang CY, Pletcher M, Lai JC, Cullaro G, Ge J| | PubMed
  6. Oral LPCN 1148 improves sarcopenia and hepatic encephalopathy in male patients with cirrhosis: A randomized, placebo-controlled phase 2 trial.
    Bruno BJ, Weavil JC, Ogle J, Chidambaram N, Carey EJ, Danford CJ, Fricker ZP, Galati JS, Lee WM, Mantry PS, Shetty K, DelConte A, Patel MV, Lai JC, Sanyal AJ| | PubMed
  7. Portal Hypertensive Gastropathy and MELD-Na Score Predict Recurrent Gastrointestinal Bleeding After TIPSS: An ALTA Group Study.
    Hu K, Sedki M, Kwong A, Kesselman A, Kolli KP, Morelli G, Spengler E, Said A, Lai J, Desai A, Paul S, Frenette C, Fallon M, German M, Verna E, Boike J, Gregory D, Thornburg B, VanWagner L, Goel A, Advancing Liver Therapeutic Approaches (ALTA) Study Group| | PubMed
  8. Novel autoantibody targets identified in patients with autoimmune hepatitis (AIH) by PhIP-Seq reveals pathogenic insights.
    Klepper A, Asaki J, Kung AF, Vazquez SE, Bodansky A, Mitchell A, Mann SA, Zorn K, Avila-Vargas I, Kari S, Tekeste M, Castro J, Lee B, Duarte M, Khalili M, Yang M, Wolters P, Price J, Perito E, Feng S, Maher JJ, Lai JC, Weiler-Normann C, Lohse AW, DeRisi J, Tana M| | PubMed
  9. Psychological Distress is Prevalent and Interdependent Among Patients with Decompensated Cirrhosis and Their Caregivers.
    Ufere NN, Zeng C, Donlan J, Shalev D, Kaplan A, Noll A, Liu A, Pintro K, Horick N, Indriolo T, Li L, Zhu E, Armstrong ME, Mason N, Engel KG, Rowland M, O'Brien K, Kenimer S, Diop MS, Jackson V, Lai JC, Chung RT, Jacobs JM, Edelen M, El-Jawahri A| | PubMed
  10. A patient-centered approach to dietary supplements for patients with chronic liver disease.
    Lai JC, Ring M, Dhruva A, Yeh GY| | PubMed
  11. Evaluating the positive predictive value of code-based identification of cirrhosis and its complications utilizing GPT-4.
    Far AT, Bastani A, Lee A, Gologorskaya O, Huang CY, Pletcher MJ, Lai JC, Ge J| | PubMed
  12. Predictors of long-term clinical outcomes after TIPS: An ALTA group study.
    Nobel YR, Boike JR, Mazumder NR, Thornburg B, Hoffman R, Kolli KP, Fallon M, Lai JC, Morelli G, Spengler EK, Said A, Desai AP, Paul S, Goel A, Hu K, Frenette C, Gregory D, Padilla C, Zhang Y, VanWagner LB, Verna EC, Advancing Liver Therapeutic Approaches (ALTA) Study Group| | PubMed
  13. Investigating the Association between Steatotic Liver Disease and CKD in a Nationally Representative Sample.
    Lai M, Lai JC, Allegretti AS, Patidar KR, Cullaro G| | PubMed
  14. Challenges in Liver Transplantation for Hepatocellular Carcinoma: A Review of Current Controversies.
    Mauro E, Sanduzzi-Zamparelli M, Jutras G, Garcia R, Soler Perromat A, Llarch N, Holguin Arce V, Ruiz P, Rimola J, Lopez E, Ferrer-Fàbrega J, García-Criado Á, Colmenero J, Lai JC, Forner A| | PubMed
  15. Decreasing Case Fatality Rates for Patients With Cirrhosis Infected With SARS-CoV-2: A National COVID Cohort Collaborative Study.
    Ge J, Far AT, Digitale JC, Pletcher MJ, Lai JC, National COVID Cohort Collaborative (N3C) Consortium| | PubMed
  16. Cystatin C and the difference between cystatin C and serum creatinine: Improved metrics to predict waitlist mortality among patients with decompensated cirrhosis.
    Cullaro G, Allegretti AS, Patidar KR, Verna EC, Lai JC| | PubMed
  17. Liver transplantation provides survival benefit at all levels of frailty: From the Multicenter Functional Assessment in Liver Transplantation Study.
    Wang M, Chiou SH, Ganger D, Ruck J, Huang CY, Kappus MR, King EA, Ladner DP, Rahimi RS, Duarte-Rojo A, Volk ML, Tevar AD, Verna EC, Lai JC| | PubMed
  18. The Liver Frailty Index enhances mortality risk prediction above and beyond MELD 3.0 alone.
    Wang M, Shui AM, Huang CY, Kappus MR, Rahimi R, Verna EC, Ruck J, King EA, Ladner DP, Tevar AD, Volk ML, Duarte-Rojo A, Ganger D, Lai JC| | PubMed
  19. From prognostication to therapeutics: Four key questions to accelerate the development of therapeutics for patients with acute-on-chronic liver failure.
    Lai JC, Sarin SK, Gines P| | PubMed
  20. The Complex Relationship Between Pain, Mental Health, and Quality-of-Life in Patients With Cirrhosis Undergoing Liver Transplant Evaluation.
    Wong RJ, Loeb R, Seal KH, Barry F, Stark Kent D, Seetharaman S, Sharma A, Lai JC, Rubin JB| | PubMed
  21. Association between protein-energy malnutrition and healthcare use among adult patients after liver transplantation: A retrospective cohort study.
    Wang M, Shui AM, Rubin JB, Pyrsopoulos N, Lai JC| | PubMed
  22. Reply: Refining retrieval and chunking strategies for enhanced clinical reliability of large language models in liver disease.
    Ge J, Sun S, Owens J, Galvez V, Gologorskaya O, Lai JC, Pletcher MJ, Lai K| | PubMed
  23. Associations between hospital-level socioeconomic patient mix and rates of central line-associated bloodstream infections in short bowel syndrome: A retrospective cohort study.
    Gutierrez SA, Chiou SH, Raghu V, Cole CR, Rhee S, Lai JC, Wadhwani SI| | PubMed
  24. Clinically relevant cut-points for changes in the Liver Frailty Index are associated with waitlist mortality in patients with cirrhosis.
    Wang M, Shui AM, Ruck J, Huang CY, Verna EC, King EA, Ladner DP, Ganger D, Kappus M, Rahimi R, Tevar AD, Duarte-Rojo A, Lai JC| | PubMed
  25. Caregiver-reported symptom burden and preferences for therapeutic goals in pediatric primary sclerosing cholangitis.
    Shifman HP, Hatchett J, Pai RA, Safer R, Gomel R, Vyas M, Li M, Lai JC, Wadhwani SI| | PubMed
  26. The Liver Frailty Index: a model for establishing organ-specific frailty metrics across all solid organ transplantation.
    Jutras G, Lai JC| | PubMed
  27. The burden of significant pain in the cirrhosis population: Risk factors, analgesic use, and impact on health care utilization and clinical outcomes.
    Rubin JB, Loeb R, Fenton C, Huang CY, Keyhani S, Seal KH, Lai JC| | PubMed
  28. Patient-focused drug development in primary sclerosing cholangitis: Insights on patient priorities and involvement in clinical trials.
    Li M, Pai RA, Gomel R, Vyas M, Callif SC, Hatchett J, Bowlus CL, Lai JC| | PubMed
  29. Applying Metabolomics and Aptamer-based Proteomics to Determine Pathophysiologic Differences in Decompensated Cirrhosis Patients Hospitalized with Acute Kidney Injury.
    Cullaro G, Allegretti AS, Patidar KR, Verna EC, Lai JC| | PubMed
  30. The influence of neighborhood income on healthcare utilization in pediatric liver transplant.
    Gutierrez SA, Chiou SH, Rhee S, Lai JC, Wadhwani SI| | PubMed
  31. Frailty, Sarcopenia, and Nutrition in Patients With Cirrhosis.
    Lai JC| | PubMed
  32. Nutritional aspects of prehabilitation in adults with cirrhosis awaiting liver transplant.
    Cruz C, Prado CM, Gillis C, Martindale R, Bémeur C, Lai JC, Tandon P| | PubMed
  33. Outpatient mean arterial pressure: A potentially modifiable risk for acute kidney injury and death among patients with cirrhosis.
    Cullaro G, Chiou SH, Fenton C, Ge J, McCulloch CE, Rubin J, Shui AM, Yao F, Lai JC| | PubMed
  34. Quality measures in pre-liver transplant care by the Practice Metrics Committee of the American Association for the Study of Liver Diseases.
    Brahmania M, Kuo A, Tapper EB, Volk ML, Vittorio JM, Ghabril M, Morgan TR, Kanwal F, Parikh ND, Martin P, Mehta S, Winder GS, Im GY, Goldberg D, Lai JC, Duarte-Rojo A, Paredes AH, Patel AA, Sahota A, McElroy LM, Thomas C, Wall AE, Malinis M, Aslam S, Simonetto DA, Ufere NN, Ramakrishnan S, Flynn MM, Ibrahim Y, Asrani SK, Serper M| | PubMed
  35. The association between mean arterial pressure and acute kidney injury reversal among patients with decompensated cirrhosis.
    Cullaro G, Allegretti AS, Fenton C, Ge J, Patidar KR, Rubin J, Sharma A, Lai JC| | PubMed
  36. Caregiver Perceptions of Social Risk Screening in Pediatric Liver Transplantation: From the Multicenter SOCIAL-Tx Study.
    Wadhwani SI, Kruse G, Squires J, Ebel N, Gupta N, Campbell K, Hsu E, Zielsdorf S, Vittorio J, Desai DM, Bucuvalas JC, Gottlieb LM, Lai JC| | PubMed
  37. Prompt Engineering for Generative Artificial Intelligence in Gastroenterology and Hepatology.
    Ge J, Chen IY, Pletcher MJ, Lai JC| | PubMed
  38. Development of a liver disease-specific large language model chat interface using retrieval-augmented generation.
    Ge J, Sun S, Owens J, Galvez V, Gologorskaya O, Lai JC, Pletcher MJ, Lai K| | PubMed
  39. Applying human-centered design to the construction of a cirrhosis management clinical decision support system.
    Ge J, Buenaventura A, Berrean B, Purvis J, Fontil V, Lai JC, Pletcher MJ| | PubMed
  40. Outcomes of High-Grade Immune Checkpoint Inhibitor Hepatitis in Hospitalized and Nonhospitalized Patients.
    Li M, Wong D, Sack JS, Vogel AS, Hodi FS, Fong L, Lai JC, Zucker SD, Grover S| | PubMed
  41. A modified Hospital Frailty Risk Score for patients with cirrhosis undergoing abdominal operations.
    Calthorpe L, Chiou SH, Rubin J, Huang CY, Feng S, Lai J| | PubMed
  42. Financial burden following adult liver transplantation is common and associated with adverse recipient outcomes.
    Ufere NN, Serper M, Kaplan A, Horick N, Indriolo T, Li L, Satapathy N, Donlan J, Castano Jimenez JC, Lago-Hernandez C, Lieber S, Gonzalez C, Keegan E, Schoener K, Bethea E, Dageforde LA, Yeh H, El-Jawahri A, Park ER, Vodkin I, Schonfeld E, Nipp R, Desai A, Lai JC| | PubMed
  43. Prevalence and Appropriateness of Polypharmacy in Older Adults with Inflammatory Bowel Diseases.
    Kochar B, Rusher A, Araka E, Glasser R, Lai J, Ritchie C, Ananthakrishnan AN| | PubMed
  44. Association of biological aging with frailty and post-transplant outcomes among adults with cirrhosis.
    LaHue SC, Fuentealba M, Roa Diaz S, Seetharaman S, Garcia T, Furman D, Lai JC, Newman JC| | PubMed
  45. A pragmatic tool to screen for pre-transplant cognitive impairment among potential candidates for liver transplant.
    Teles MS, Ruck JM, Jefferis A, Helmy S, Oh ES, Murriel EC, Lai JC, King EA| | PubMed
  46. Caregivers' and providers' perspectives of social and medical care after pediatric liver transplant: Results from the multicenter SOCIAL-Tx study.
    Wadhwani SI, Alvarado A, Shifman HP, Bautista B, Yalung J, Squires JE, Campbell K, Ebel NH, Hsu E, Vittorio J, Zielsdorf S, Desai DM, Bucuvalas JC, Gottlieb L, Kotagal U, Lyles CR, Ackerman SL, Lai JC| | PubMed
  47. A Comparison of a Large Language Model vs Manual Chart Review for the Extraction of Data Elements From the Electronic Health Record.
    Ge J, Li M, Delk MB, Lai JC| | PubMed
  48. Prevalence of cognitive impairment in liver transplant recipients.
    Berry K, Ruck JM, Barry F, Shui AM, Cortella A, Kent D, Seetharaman S, Wong R, VandeVrede L, Lai JC| | PubMed
  49. Barriers and Facilitators to Exercise in Older Adults Awaiting Kidney Transplantation and Their Care Partners.
    Sheshadri A, Elia JR, Garcia G, Abrams G, Adey DB, Lai JC, Sudore RL| | PubMed
  50. The liver frailty index is a predictor of healthcare utilization after liver transplantation in older adults.
    Wang M, Shui AM, Ruck J, King E, Rahimi R, Kappus M, Volk ML, Ganger DR, Ladner DP, Duarte-Rojo A, Huang CY, Verna EC, Lai JC| | PubMed
  51. Association of body mass index with post-liver transplant outcomes.
    Ruck JM, Shui AM, Jefferis AA, Duarte Rojo A, Rahimi RS, Ganger DR, Verna EC, Kappus M, Ladner DP, Segev DL, Volk M, Tevar A, King EA, Lai JC| | PubMed
  52. Development of a Liver Disease-Specific Large Language Model Chat Interface using Retrieval Augmented Generation.
    Ge J, Sun S, Owens J, Galvez V, Gologorskaya O, Lai JC, Pletcher MJ, Lai K| | PubMed
  53. Association between neighborhood-based material deprivation and liver transplant waitlist registrants demographics and mortality.
    Cullaro G, Ge J, Lee BP, Lai JC, Wadhwani SI| | PubMed
  54. Neighborhood Income Is Associated with Health Care Use in Pediatric Short Bowel Syndrome.
    Gutierrez SA, Pathak S, Raghu V, Shui A, Huang CY, Rhee S, McKenzie-Sampson S, Lai JC, Wadhwani SI| | PubMed
  55. A chair-stand time of greater than 15 seconds is associated with an increased risk of death and hospitalization in cirrhosis.
    Nguyen VV, Wang S, Whitlock R, Xu C, Taneja S, Singh S, Abraldes JG, Burak K, Bailey RJ, Grab JD, Lai JC, Tandon P| | PubMed
  56. Ambient air pollution is associated with graft failure/death in pediatric liver transplant recipients.
    Yalung JE, Shifman HP, Manning ER, Beck A, Bucuvalas J, Lai JC, Wadhwani SI| | PubMed
  57. Association of state Medicaid expansion policies with pediatric liver transplant outcomes.
    Shifman HP, Huang CY, Beck AF, Bucuvalas J, Perito ER, Hsu EK, Ebel NH, Lai JC, Wadhwani SI| | PubMed
  58. Nonselective beta-blockers may lead to stage 2 acute kidney injury and waitlist mortality in child class C cirrhosis.
    Lai M, Fenton C, Ge J, Rubin J, Lai JC, Cullaro G| | PubMed
  59. Variation in skeletal muscle mass among patients with cirrhosis of different self-identified race/ethnicity.
    Ha NB, Fan B, Seetharaman S, Kent DS, Yao F, Shui AM, Huang CY, Wadhwani SI, Lai JC| | PubMed
  60. Structured Moderate Exercise and Biomarkers of Kidney Health in Sedentary Older Adults: The Lifestyle Interventions and Independence for Elders Randomized Clinical Trial.
    Sheshadri A, Lai M, Hsu FC, Bauer SR, Chen SH, Tse W, Jotwani V, Tranah GJ, Lai JC, Hallan S, Fielding RA, Liu C, Ix JH, Coca SG, Shlipak MG| | PubMed
  61. A comparison of large language model versus manual chart review for extraction of data elements from the electronic health record.
    Ge J, Li M, Delk MB, Lai JC| | PubMed
  62. Systematic Review and Meta-Analysis of Brief Cognitive Instruments to Evaluate Suspected Dementia in Chinese-Speaking Populations.
    Yu RC, Lai JC, Hui EK, Mukadam N, Kapur N, Stott J, Livingston G| | PubMed
  63. Predicting post-liver transplant outcomes in patients with acute-on-chronic liver failure using Expert-Augmented Machine Learning.
    Ge J, Digitale JC, Fenton C, McCulloch CE, Lai JC, Pletcher MJ, Gennatas ED| | PubMed
  64. Clinical decision support and electronic interventions to improve care quality in chronic liver diseases and cirrhosis.
    Ge J, Fontil V, Ackerman S, Pletcher MJ, Lai JC| | PubMed
  65. Racial and Ethnic Disparities Among Patients Hospitalized for Acute Cholangitis in the United States.
    Wang M, Wadhwani SI, Cullaro G, Lai JC, Rubin JB| | PubMed
  66. Brief PROMIS Assessment Screens for Frailty and Predicts Hospitalizations in Liver Transplant Candidates.
    Thuluvath AJ, Duarte-Rojo A, Lai JC, Peipert J, Dietch ZC, Siddiqui O, Morrissey S, Belfanti K, Zhao L, Guo K, Nizamuddin M, Polineni P, Levitsky J, Flores AM, Ladner DP| | PubMed
  67. Reply: What is the actual role of decompensated cirrhosis in the breakthrough SARS-CoV-2 infection?
    Ge J, Digitale JC, Pletcher MJ, Lai JC| | PubMed
  68. Caregiver Burden in Adult Solid Organ Transplantation.
    Deng LX, Sharma A, Gedallovich SM, Tandon P, Hansen L, Lai JC| | PubMed
  69. Clinical Characteristics Associated With Posttransplant Survival Among Adults 70 Years Old or Older Undergoing Liver Transplantation.
    Wang M, Ge J, Ha N, Shui AM, Huang CY, Cullaro G, Lai JC| | PubMed
  70. Time to embrace PROMIS-29 as the standard health-related quality of life instrument for patients with cirrhosis.
    Tapper EB, Lai JC| | PubMed
  71. Early Liver Specialist Consultation is Associated With Faster Biochemical Resolution of Severe Immune Checkpoint Inhibitor-Induced Hepatitis.
    Li M, Wong D, Sack JS, Vogel AS, Hodi FS, Fong L, Lai JC, Grover S, Zucker SD| | PubMed
  72. Targets and study design for symptom-focused trials aimed at patients with cirrhosis: An expert consensus.
    Patel AA, Tapper EB, Kanwal F, Woodrell CD, Hansen L, Lai JC, Rogal S, McDermott C, Rakoski M, Ufere NN| | PubMed
  73. Change in Platelet Count after Transjugular Intrahepatic Portosystemic Shunt Creation: An Advancing Liver Therapeutic Approaches (ALTA) Group Study.
    Wong RJ, Ge J, Boike J, German M, Morelli G, Spengler E, Said A, Desai A, Couri T, Paul S, Frenette C, Verna EC, Goel A, Fallon M, Thornburg B, VanWagner L, Lai JC, Kolli KP| | PubMed
  74. Actionable Solutions to Achieve Health Equity in Chronic Liver Disease.
    Jones PD, Lai JC, Bajaj JS, Kanwal F| | PubMed
  75. The tele-liver frailty index (TeLeFI): development of a novel frailty tool in patients with cirrhosis via telemedicine.
    Wang M, Shui AM, Barry F, Verna E, Kent D, Yao F, Seetharaman S, Berry K, Grubbs RK, George G, Huang CY, Duarte-Rojo A, Lai JC| | PubMed
  76. Artificial intelligence-based text generators in hepatology: ChatGPT is just the beginning.
    Ge J, Lai JC| | PubMed
  77. Serum and plasma protein biomarkers associated with frailty in patients with cirrhosis.
    Ha NB, Seetharaman S, Kent DS, Yao F, Shui AM, Huang CY, Walston J, Lai JC| | PubMed
  78. Breakthrough SARS-CoV-2 infection outcomes in vaccinated patients with chronic liver disease and cirrhosis: A National COVID Cohort Collaborative study.
    Ge J, Digitale JC, Pletcher MJ, Lai JC, N3C Consortium| | PubMed
  79. Women with cirrhosis have lower self-rated health than men.
    Wang M, Huang CY, Cullaro G, Covinsky K, Lai JC| | PubMed
  80. Association of Frailty With Health-Related Quality of Life in Liver Transplant Recipients.
    Lai JC, Shui AM, Duarte-Rojo A, Rahimi RS, Ganger DR, Verna EC, Volk ML, Kappus M, Ladner DP, Boyarsky B, Segev DL, Gao Y, Huang CY, Singer JP| | PubMed
  81. Promoting Prognostic Understanding and Health Equity for Patients With Advanced Liver Disease: Using "Best Case/Worst Case".
    Ufere NN, El-Jawahri A, Ritchie C, Lai JC, Schwarze ML| | PubMed
  82. Promoting Prognostic Understanding and Health Equity for Patients With Advanced Liver Disease: Using "Best Case/Worst Case".
    Ufere NN, El-Jawahri A, Ritchie C, Lai JC, Schwarze ML| | PubMed
  83. The impact of right atrial pressure on outcomes in patients undergoing TIPS, an ALTA group study.
    Bommena S, Mahmud N, Boike JR, Thornburg BG, Kolli KP, Lai JC, German M, Morelli G, Spengler E, Said A, Desai AP, Junna S, Paul S, Frenette C, Verna EC, Goel A, Gregory D, Padilla C, VanWagner LB, Fallon MB, Advancing Liver Therapeutic Approaches (ALTA) Study Group| | PubMed
  84. Introducing Norah Terrault, MD, MPH, Our 2023 AASLD President.
    Peters MG, Lai JC| | PubMed
  85. Addressing sex-based disparities in solid organ transplantation in the United States - a conference report.
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  86. CT-quantified sarcopenic visceral obesity is associated with poor transplant waitlist mortality in patients with cirrhosis.
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  87. Cirrhosis Inpatients Receive More Opioids and Fewer Nonopioid Analgesics Than Patients Without Cirrhosis.
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  88. Multicenter assessment of hypertension management among liver transplantation recipients.
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  89. Response to: "Towards optimally replacing the current version of MELD".
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  90. Predictors of Length of Stay and Mortality During Simultaneous Liver-Kidney Transplant Index Admission: Results From the US-Multicenter SLKT Consortium.
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  91. Role of Oral Health, Frailty, and Minimal Hepatic Encephalopathy in the Risk of Hospitalization: A Prospective Multi-Center Cohort of Outpatients With Cirrhosis.
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  92. Factors associated with cardiovascular events after simultaneous liver-kidney transplant from the US Multicenter Simultaneous Liver-Kidney Transplant Consortium.
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  93. Understanding Current Limitations to Exercise Interventions After Liver Transplantation.
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  94. Which preoperative assessment modalities best identify patients who are suitable for enhanced recovery after liver transplantation? A systematic review of the literature and expert panel recommendations.
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  95. Personality Traits in Patients With Cirrhosis Are Different From Those of the General Population and Impact Likelihood of Liver Transplantation.
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  96. Leveraging a New ICD-10 Diagnosis Code to Characterize Hospitalized Patients With Primary Sclerosing Cholangitis.
    Wang M, Auerbach A, Oreper SM, Hohmann SF, Lai JC, Rubin JB| | PubMed
  97. Association of serum metabolites and gut microbiota at hospital admission with nosocomial infection development in patients with cirrhosis.
    Bajaj JS, Reddy KR, Tandon P, Garcia-Tsao G, Kamath PS, O'Leary JG, Wong F, Lai J, Vargas H, Thuluvath PJ, Subramanian RM, Pena-Rodriguez M, Sikaroodi M, Thacker LR, Gillevet PM| | PubMed
  98. Novel approaches are needed to study social determinants of health in liver transplantation.
    Ge J, Lai JC, Wadhwani SI| | PubMed
  99. Medical Need and Transplant Accessibility-Reply.
    Wadhwani SI, Lai JC, Gottlieb L| | PubMed
  100. Hepatic and renal function impact concentrations of plasma biomarkers of neuropathology.
    Berry K, Asken BM, Grab JD, Chan B, Lario Lago A, Wong R, Seetharaman S, LaHue SC, Possin KL, Rojas JC, Kramer JH, Boxer AL, Lai JC, VandeVrede L| | PubMed
  101. Breakthrough SARS-CoV-2 Infection Outcomes in Vaccinated Patients with Chronic Liver Disease and Cirrhosis: A National COVID Cohort Collaborative Study.
    Ge J, Digitale JC, Pletcher MJ, Lai JC, N3C Consortium| | PubMed
  102. Financial burden in adults with chronic liver disease: A scoping review.
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  103. Burden of early hospitalization after simultaneous liver-kidney transplantation: Results from the US Multicenter SLKT Consortium.
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  104. The digital determinants of liver disease.
    Wadhwani SI, Lai JC| | PubMed
  105. Caregiver perspectives on the everyday medical and social needs of long-term pediatric liver transplant patients.
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  106. "Beyond MELD" - Emerging strategies and technologies for improving mortality prediction, organ allocation and outcomes in liver transplantation.
    Ge J, Kim WR, Lai JC, Kwong AJ| | PubMed
  107. Conceptualizing a Traditional Chinese Medicine and Pathology of Arousal Diagnostic and Pathophysiological Framework for Postacute Sequelae of COVID-19.
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  108. Improvement in Long-COVID Symptoms Using Acupuncture: A Case Study.
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  109. Sarcopenic visceral obesity is associated with increased post-liver transplant mortality in acutely ill patients with cirrhosis.
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  110. Loneliness in adults awaiting liver transplantation at 7 U.S. transplant centers.
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  111. A review of racial, socioeconomic, and geographic disparities in pediatric liver transplantation.
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  112. Medical Need, Financial Resources, and Transplant Accessibility.
    Wadhwani SI, Lai JC, Gottlieb LM| | PubMed
  113. Admission Serum Metabolites and Thyroxine Predict Advanced Hepatic Encephalopathy in a Multicenter Inpatient Cirrhosis Cohort.
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  114. Variability in serum creatinine is associated with waitlist and post-liver transplant mortality in patients with cirrhosis.
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  115. Improving the Model for End-Stage Liver Disease with sodium by incorporating kidney dysfunction types.
    Cullaro G, Verna EC, McCulloch CE, Lai JC| | PubMed
  116. The bidirectional relationship between nonalcoholic fatty liver disease and sarcopenia.
    Ha NB, Lai JC| | PubMed
  117. Acute-on-Chronic Liver Failure.
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  118. Association of Primary Care Shortage Areas with Adverse Outcomes after Pediatric Liver Transplant.
    Shifman HP, Rasnick E, Huang CY, Beck AF, Bucuvalas J, Lai JC, Wadhwani SI| | PubMed
  119. Perioperative Delta Sodium and Post-Liver Transplant Neurological Complications in Liver Transplant Recipients.
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  120. Top Ten Tips Palliative Care Clinicians Should Know About Solid Organ Transplantation.
    Murakami N, Baggett ND, Schwarze ML, Ladin K, Courtwright AM, Goldberg HJ, Nolley EP, Jain N, Landzberg M, Wentlandt K, Lai JC, Shinall MC, Ufere NN, Jones CA, Lakin JR| | PubMed
  121. Osmotic Demyelination Syndrome in Hospitalized Patients With Cirrhosis: Analysis of the National Inpatient Sample (NIS).
    Berry K, Rubin JB, Lai JC| | PubMed
  122. Implicit bias and the gender inequity in liver transplantation.
    Lai JC, Pomfret EA, Verna EC| | PubMed
  123. Acute-on-Chronic Liver Failure Clinical Guidelines.
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  124. Prognosis of hospitalized patients with cirrhosis and acute kidney disease.
    Wong F, Garcia-Tsao G, Reddy KR, O'Leary JG, Kamath PS, Tandon P, Lai JC, Vargas HE, Biggins SW, Fallon MB, Thuluvath PJ, Maliakkal BJ, Subramanian R, Thacker L, Bajaj JS| | PubMed
  125. Reply.
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  126. Long-Term Opioid Use Among Veterans with Cirrhosis: High-Dose Prescriptions in an Exceedingly High-Risk Population.
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  127. The 5Ms of Geriatrics in Gastroenterology: The Path to Creating Age-Friendly Care for Older Adults With Inflammatory Bowel Diseases and Cirrhosis.
    Kochar B, Ufere NN, Ritchie CS, Lai JC| | PubMed
  128. Frailty, mortality, and health care utilization after liver transplantation: From the Multicenter Functional Assessment in Liver Transplantation (FrAILT) Study.
    Lai JC, Shui AM, Duarte-Rojo A, Ganger DR, Rahimi RS, Huang CY, Yao F, Kappus M, Boyarsky B, McAdams-Demarco M, Volk ML, Dunn MA, Ladner DP, Segev DL, Verna EC, Feng S, from the Multi-Center Functional Assessment in Liver Transplantation (FrAILT) Study| | PubMed
  129. Racial/ethnic disparities in wait-list outcomes are only partly explained by socioeconomic deprivation among children awaiting liver transplantation.
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  130. Frailty is associated with increased risk of cirrhosis disease progression and death.
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  131. Frailty is strongly associated with self-reported symptom burden among patients with cirrhosis.
    Deng LX, Bischoff KE, Kent DS, O'Riordan DL, Pantilat SZ, Lai JC| | PubMed
  132. An Analysis of Free-Text Refusals as an Indicator of Readiness to Accept Organ Offers in Liver Transplantation.
    Ge J, Ku E, Roll GR, Lai JC| | PubMed
  133. The Prediction of In-Hospital Mortality in Decompensated Cirrhosis with Acute-on-Chronic Liver Failure.
    Wong F, Reddy KR, Tandon P, Lai JC, Jagarlamudi N, Weir V, Kok B, Kalainy S, Srisengfa YT, Albhaisi S, Reuter B, Acharya C, Shaw J, Thacker LR, Bajaj JS| | PubMed
  134. Sex-based Disparities in Hepatocellular Carcinoma Recurrence After Liver Transplantation.
    Cullaro G, Rubin J, Mehta N, Yao F, Verna EC, Lai JC| | PubMed
  135. Pilot Randomized Controlled Trial of an Advance Care Planning Video Decision Tool for Patients With Advanced Liver Disease.
    Ufere NN, Robinson B, Donlan J, Indriolo T, Bloom J, Scherrer A, Mason NM, Patel A, Lai JC, Chung RT, Volandes A, El-Jawahri A| | PubMed
  136. Frailty and the Risk of Acute Kidney Injury Among Patients With Cirrhosis.
    Cullaro G, Verna EC, Duarte-Rojo A, Kappus MR, Ganger DR, Rahimi RS, Boyarsky B, Segev DL, McAdams-DeMarco M, Ladner DP, Volk ML, Hsu CY, Lai JC| | PubMed
  137. Frailty and Risk of Serious Infections in Biologic-treated Patients With Inflammatory Bowel Diseases.
    Singh S, Heien HC, Sangaralingham L, Shah ND, Lai JC, Sandborn WJ, Moore AA| | PubMed
  138. Addressing Social Adversity to Improve Outcomes for Children After Liver Transplant.
    Wadhwani SI, Gottlieb L, Bucuvalas JC, Lyles C, Lai JC| | PubMed
  139. Outcomes After TIPS for Ascites and Variceal Bleeding in a Contemporary Era-An ALTA Group Study.
    Boike JR, Mazumder NR, Kolli KP, Ge J, German M, Jest N, Morelli G, Spengler E, Said A, Lai JC, Desai AP, Couri T, Paul S, Frenette C, Verna EC, Rahim U, Goel A, Gregory D, Thornburg B, VanWagner LB, Advancing Liver Therapeutic Approaches (ALTA) Study Group| | PubMed
  140. Thinking Ahead: Advance Care Planning for Patients With Cirrhosis.
    Deng LX, Tana MM, Lai JC| | PubMed
  141. Malnutrition, Frailty, and Sarcopenia in Patients With Cirrhosis: 2021 Practice Guidance by the American Association for the Study of Liver Diseases.
    Lai JC, Tandon P, Bernal W, Tapper EB, Ekong U, Dasarathy S, Carey EJ| | PubMed
  142. Correcting the sex disparity in access to liver transplantation: Lest perfect be the enemy of better.
    Kwong AJ, Lai JC, Kim WR| | PubMed
  143. Cognitive Impairment and Physical Frailty in Patients With Cirrhosis.
    Berry K, Duarte-Rojo A, Grab JD, Dunn MA, Boyarsky BJ, Verna EC, Kappus MR, Volk ML, McAdams-DeMarco M, Segev DL, Ganger DR, Ladner DP, Shui A, Tincopa MA, Rahimi RS, Lai JC, from the Multi-Center Functional Assessment in Liver Transplantation (FrAILT) Study| | PubMed
  144. Temporal Trends and Evolving Outcomes After Simultaneous Liver-Kidney Transplantation: Results from the US SLKT Consortium.
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  145. Symptom Burden Is Associated with Increased Emergency Department Utilization among Patients with Cirrhosis.
    Deng LX, Kent DS, O'Riordan DL, Pantilat SZ, Lai JC, Bischoff KE| | PubMed
  146. Inpatient Frailty Assessment Is Feasible and Predicts Nonhome Discharge and Mortality in Decompensated Cirrhosis.
    Serper M, Tao SY, Kent DS, Garren P, Burdzy AE, Lai JC, Gougol A, Bloomer PM, Reddy KR, Dunn MA, Duarte-Rojo A| | PubMed
  147. Association Between Kidney Dysfunction Types and Mortality Among Hospitalized Patients with Cirrhosis.
    Cullaro G, Rubin JB, Fortune BE, Crawford CV, Verna EC, Hsu CY, Liu KD, Brown RS, Lai JC, Rosenblatt R| | PubMed
  148. Outcomes of SARS-CoV-2 Infection in Patients With Chronic Liver Disease and Cirrhosis: A National COVID Cohort Collaborative Study.
    Ge J, Pletcher MJ, Lai JC, N3C Consortium| | PubMed
  149. The relationship between frailty and cirrhosis etiology: From the Functional Assessment in Liver Transplantation (FrAILT) Study.
    Xu CQ, Mohamad Y, Kappus MR, Boyarsky B, Ganger DR, Volk ML, Rahimi RS, Duarte-Rojo A, McAdams-DeMarco M, Segev DL, Ladner DP, Verna EC, Grab J, Tincopa M, Dunn MA, Lai JC| | PubMed
  150. Admission Urinary and Serum Metabolites Predict Renal Outcomes in Hospitalized Patients With Cirrhosis.
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  151. Sarcopenia and frailty in decompensated cirrhosis.
    Tandon P, Montano-Loza AJ, Lai JC, Dasarathy S, Merli M| | PubMed
  152. Developing Priorities for Palliative Care Research in Advanced Liver Disease: A Multidisciplinary Approach.
    Patel AA, Woodrell C, Ufere NN, Hansen L, Tandon P, Verma M, Lai J, Pinotti R, Rakoski M, and on behalf of the Palliative Care Education, Advocacy, and Research in Liver Disease (PEARL) Wor| | PubMed
  153. Visceral Adipose Tissue Inflammation and Radiographic Visceral-to-Subcutaneous Adipose Tissue Ratio in Patients with Cirrhosis.
    Ha NB, Cho SJ, Mohamad Y, Kent D, Jun G, Wong R, Swarnakar V, Lin S, Maher JJ, Lai JC| | PubMed
  154. Outcomes of SARS-CoV-2 Infection in Patients with Chronic Liver Disease and Cirrhosis: a N3C Study.
    Ge J, Pletcher MJ, Lai JC, N3C Consortium| | PubMed
  155. Association of Cognitive Function Screening Results with Adherence and Performance in a Pedometer-Based Intervention.
    Sheshadri A, Kittiskulnam P, Delgado C, Sudore RL, Lai JC, Johansen KL| | PubMed
  156. Advance Care Planning in Liver Transplant-Preparing for Both Life and Death.
    Ufere NN, Lai JC| | PubMed
  157. Renal Outcomes After Simultaneous Liver-Kidney Transplantation: Results from the US Multicenter Simultaneous Liver-Kidney Transplantation Consortium.
    Sharma P, Sui Z, Zhang M, Magee JC, Barman P, Patel Y, Schluger A, Walter K, Biggins SW, Cullaro G, Wong R, Lai JC, Jo J, Sinha J, VanWagner L, Verna EC| | PubMed
  158. A Multicenter Pilot Randomized Clinical Trial of a Home-Based Exercise Program for Patients With Cirrhosis: The Strength Training Intervention (STRIVE).
    Lai JC, Dodge JL, Kappus MR, Wong R, Mohamad Y, Segev DL, McAdams-DeMarco M| | PubMed
  159. Early Kidney Allograft Failure After Simultaneous Liver-kidney Transplantation: Evidence for Utilization of the Safety Net?
    Cullaro G, Verna EC, Emond JC, Orandi BJ, Mohan S, Lai JC| | PubMed
  160. Patterns of Inpatient Opioid Use and Related Adverse Events Among Patients With Cirrhosis: A Propensity-Matched Analysis.
    Rubin JB, Lai JC, Shui AM, Hohmann SF, Auerbach A| | PubMed
  161. A Methodology to Generate Longitudinally Updated Acute-On-Chronic Liver Failure Prognostication Scores From Electronic Health Record Data.
    Ge J, Najafi N, Zhao W, Somsouk M, Fang M, Lai JC| | PubMed
  162. Center variation in long-term outcomes for socioeconomically deprived children.
    Wadhwani SI, Huang CY, Gottlieb L, Beck AF, Bucuvalas J, Kotagal U, Lyles C, Lai JC| | PubMed
  163. Renal Recovery and Mortality Risk among Patients with Hepatorenal Syndrome Receiving Chronic Maintenance Dialysis.
    McAllister S, Lai JC, Copeland TP, Johansen KL, McCulloch CE, Kwong YD, Seth D, Grimes B, Ku E| | PubMed
  164. Association of Frailty and Sex With Wait List Mortality in Liver Transplant Candidates in the Multicenter Functional Assessment in Liver Transplantation (FrAILT) Study.
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  165. Assessment of the Frail Patient With End-Stage Liver Disease: A Practical Overview of Sarcopenia, Physical Function, and Disability.
    Williams FR, Milliken D, Lai JC, Armstrong MJ| | PubMed
  166. Implementing a Height-Based Rule for the Allocation of Pediatric Donor Livers to Adults: A Liver Simulated Allocation Model Study.
    Ge J, Wood N, Segev DL, Lai JC, Gentry S| | PubMed
  167. Low Predictability of Readmissions and Death Using Machine Learning in Cirrhosis.
    Hu C, Anjur V, Saboo K, Reddy KR, O'Leary J, Tandon P, Wong F, Garcia-Tsao G, Kamath PS, Lai JC, Biggins SW, Fallon MB, Thuluvath P, Subramanian RM, Maliakkal B, Vargas H, Thacker LR, Iyer RK, Bajaj JS| | PubMed
  168. Evaluating the Associations Between the Liver Frailty Index and Karnofsky Performance Status With Waitlist Mortality.
    Xu CQ, Yao F, Mohamad Y, Wong R, Kent D, Seetharaman S, Srisengfa Y, Lai JC| | PubMed
  169. National Early Career Transplant Hepatologist Survey: Compensation, Burnout, and Job Satisfaction.
    Kriss M, Te HS, Verna EC, VanWagner LB, Scott FI, Lai JC| | PubMed
  170. Nonalcoholic Fatty Liver Disease and Diabetes Mellitus Are Associated With Post-Transjugular Intrahepatic Portosystemic Shunt Renal Dysfunction: An Advancing Liver Therapeutic Approaches Group Study.
    Ge J, Lai JC, Boike JR, German M, Jest N, Morelli G, Spengler E, Said A, Lee A, Hristov A, Desai AP, Junna S, Pokhrel B, Couri T, Paul S, Frenette C, Christian-Miller N, Laurito M, Verna EC, Rahim U, Goel A, Das A, Pine S, Gregory D, VanWagner LB, Kolli KP, Advancing Liver Therapeutic Approaches (ALTA) Study Group| | PubMed
  171. Increased Risk of ACLF and Inpatient Mortality in Hospitalized Patients with Cirrhosis and Hepatic Hydrothorax.
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  172. Kefir Peptides Prevent Estrogen Deficiency-Induced Bone Loss and Modulate the Structure of the Gut Microbiota in Ovariectomized Mice.
    Tu MY, Han KY, Chang GR, Lai GD, Chang KY, Chen CF, Lai JC, Lai CY, Chen HL, Chen CM| | PubMed
  173. Identifying an Optimal Liver Frailty Index Cutoff to Predict Waitlist Mortality in Liver Transplant Candidates.
    Kardashian A, Ge J, McCulloch CE, Kappus MR, Dunn MA, Duarte-Rojo A, Volk ML, Rahimi RS, Verna EC, Ganger DR, Ladner D, Dodge JL, Boyarsky B, McAdams-DeMarco M, Segev DL, Lai JC| | PubMed
  174. Outcomes of Liver Transplantation Among Older Recipients With Nonalcoholic Steatohepatitis in a Large Multicenter US Cohort: the Re-Evaluating Age Limits in Transplantation Consortium.
    Kwong AJ, Devuni D, Wang C, Boike J, Jo J, VanWagner L, Serper M, Jones L, Sharma R, Verna EC, Shor J, German MN, Hristov A, Lee A, Spengler E, Koteish AA, Sehmbey G, Seetharam A, John N, Patel Y, Kappus MR, Couri T, Paul S, Salgia RJ, Nhu Q, Frenette CT, Lai JC, Goel A, Re-Evaluating Age Limits in Transplantation (REALT) Consortium| | PubMed
  175. Unforeseen consequences of the COVID pandemic.
    Bucuvalas J, Lai JC| | PubMed
  176. Progression of Stage 2 and 3 Acute Kidney Injury in Patients With Decompensated Cirrhosis and Ascites.
    Wong F, Reddy KR, Tandon P, O'Leary JG, Garcia-Tsao G, Vargas HE, Lai JC, Biggins SW, Maliakkal B, Fallon M, Subramanian R, Thuluvath P, Kamath PS, Thacker L, Bajaj JS| | PubMed
  177. Neighborhood socioeconomic deprivation, racial segregation, and organ donation across 5 states.
    Wadhwani SI, Brokamp C, Rasnick E, Bucuvalas JC, Lai JC, Beck AF| | PubMed
  178. Association of motivations and barriers with participation and performance in a pedometer-based intervention.
    Sheshadri A, Kittiskulnam P, Delgado C, Sudore R, Lai JC, Johansen KL| | PubMed
  179. Psychological contributors to the frail phenotype: The association between resilience and frailty in patients with cirrhosis.
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  180. Serum Levels of Metabolites Produced by Intestinal Microbes and Lipid Moieties Independently Associated With Acute-on-Chronic Liver Failure and Death in Patients With Cirrhosis.
    Bajaj JS, Reddy KR, O'Leary JG, Vargas HE, Lai JC, Kamath PS, Tandon P, Wong F, Subramanian RM, Thuluvath P, Fagan A, White MB, Gavis EA, Sehrawat T, de la Rosa Rodriguez R, Thacker LR, Sikaroodi M, Garcia-Tsao G, Gillevet PM| | PubMed
  181. Time for Action to Address the Persistent Sex-Based Disparity in Liver Transplant Access.
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  182. Frailty as an Immune-Mediated Condition That Leads to an Increased Risk of Acute Cellular Rejection in Liver Transplant Recipients.
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  183. Liver Transplant Survivorship.
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  184. Low Rates of Advance Care Planning (ACP) Discussions Despite Readiness to Engage in ACP Among Liver Transplant Candidates.
    Wang CW, Lebsack A, Sudore RL, Lai JC| | PubMed
  185. Multicenter Study of Age, Frailty, and Waitlist Mortality Among Liver Transplant Candidates.
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  186. Aggressive utilization of liver allografts: Improved outcomes over time.
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  187. Women who undergo liver transplant have longer length of stay post-transplant compared with men.
    Rubin JB, Cullaro G, Ge J, Lai JC| | PubMed
  188. Insurance Status But Not Race and Ethnicity Are Associated With Outcomes in a Large Hospitalized Cohort of Patients With Cirrhosis.
    Bajaj JS, O'Leary JG, Tandon P, Wong F, Kamath PS, Biggins SW, Garcia-Tsao G, Lai J, Fallon MB, Thuluvath PJ, Vargas HE, Maliakkal B, Subramanian RM, Thacker LR, Reddy KR| | PubMed
  189. Physical Function, Physical Activity, and Quality of Life After Liver Transplantation.
    Dunn MA, Rogal SS, Duarte-Rojo A, Lai JC| | PubMed
  190. Association of Karnofsky Performance Status with waitlist mortality among older and younger adults awaiting kidney transplantation.
    Sheshadri A, Cullaro G, Johansen KL, Lai JC| | PubMed
  191. Chronic Kidney Disease in Liver Transplant Candidates: A Rising Burden Impacting Post-Liver Transplant Outcomes.
    Cullaro G, Verna EC, Lee BP, Lai JC| | PubMed
  192. Changes in frailty are associated with waitlist mortality in patients with cirrhosis.
    Lai JC, Dodge JL, Kappus MR, Dunn MA, Volk ML, Duarte-Rojo A, Ganger DR, Rahimi RS, McCulloch CE, Haugen CE, McAdams-DeMarco M, Ladner DP, Segev DL, Verna EC, Multi-Center Functional Assessment in Liver Transplantation (FrAILT) Study| | PubMed
  193. Effect of a pedometer-based walking intervention on body composition in patients with ESRD: a randomized controlled trial.
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  194. Underutilization of Hospice in Inpatients with Cirrhosis: The NACSELD Experience.
    O'Leary JG, Tandon P, Reddy KR, Biggins SW, Wong F, Kamath PS, Garcia-Tsao G, Maliakkal B, Lai J, Fallon M, Vargas HE, Thuluvath P, Subramanian R, Thacker LR, Bajaj JS| | PubMed
  195. Neighborhood socioeconomic deprivation is associated with worse patient and graft survival following pediatric liver transplantation.
    Wadhwani SI, Beck AF, Bucuvalas J, Gottlieb L, Kotagal U, Lai JC| | PubMed
  196. Frailty Is Associated With Increased Rates of Acute Cellular Rejection Within 3 Months After Liver Transplantation.
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  197. A Comprehensive Review of Outcome Predictors in Low MELD Patients.
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  198. Response to "Reply to: 'The decreasing predictive power of MELD in an era of changing etiology of liver disease'".
    Godfrey EL, Malik TH, Lai JC, Mindikoglu AL, Galván NTN, Cotton RT, O'Mahony CA, Goss JA, Rana A| | PubMed
  199. Gender Differences Among Patients Hospitalized With Cirrhosis in the United States.
    Rubin JB, Sundaram V, Lai JC| | PubMed
  200. Split liver transplantation is utilized infrequently and concentrated at few transplant centers in the United States.
    Ge J, Perito ER, Bucuvalas J, Gilroy R, Hsu EK, Roberts JP, Lai JC| | PubMed
  201. Association Between Liver Transplant Wait-list Mortality and Frailty Based on Body Mass Index.
    Haugen CE, McAdams-DeMarco M, Verna EC, Rahimi RS, Kappus MR, Dunn MA, Volk ML, Gurakar A, Duarte-Rojo A, Ganger DR, O'Leary JG, Ladner D, Garonzik-Wang J, Segev DL, Lai JC| | PubMed
  202. Sex Differences in the Association Between Frailty and Sarcopenia in Patients With Cirrhosis.
    Fozouni L, Wang CW, Lai JC| | PubMed
  203. Differential Impact of Age Among Liver Transplant Candidates With and Without Hepatocellular Carcinoma.
    Cullaro G, Rubin JB, Mehta N, Lai JC| | PubMed
  204. Identifying a clinically relevant cutoff for height that is associated with a higher risk of waitlist mortality in liver transplant candidates.
    Ge J, Lai JC| | PubMed
  205. Sarcopenia Predicts Post-transplant Mortality in Acutely Ill Men Undergoing Urgent Evaluation and Liver Transplantation.
    Kuo SZ, Ahmad M, Dunn MA, Montano-Loza AJ, Carey EJ, Lin S, Moghe A, Chen HW, Ebadi M, Lai JC| | PubMed
  206. Frailty and the Burden of Concurrent and Incident Disability in Patients With Cirrhosis: A Prospective Cohort Study.
    Lai JC, Dodge JL, McCulloch CE, Covinsky KE, Singer JP| | PubMed
  207. Hospitalized Women With Cirrhosis Have More Nonhepatic Comorbidities and Associated Complications Than Men.
    Rubin JB, Srisengfa YT, Albhaisi S, Acharya C, Nangia G, Shaikh T, Thacker LR, Reddy KR, Tandon P, Bajaj JS, Lai JC| | PubMed
  208. Review article: impact of exercise on physical frailty in patients with chronic liver disease.
    Williams FR, Berzigotti A, Lord JM, Lai JC, Armstrong MJ| | PubMed
  209. The decreasing predictive power of MELD in an era of changing etiology of liver disease.
    Godfrey EL, Malik TH, Lai JC, Mindikoglu AL, Galván NTN, Cotton RT, O'Mahony CA, Goss JA, Rana A| | PubMed
  210. A North American Expert Opinion Statement on Sarcopenia in Liver Transplantation.
    Carey EJ, Lai JC, Sonnenday C, Tapper EB, Tandon P, Duarte-Rojo A, Dunn MA, Tsien C, Kallwitz ER, Ng V, Dasarathy S, Kappus M, Bashir MR, Montano-Loza AJ| | PubMed
  211. Barriers to ideal outcomes after pediatric liver transplantation.
    Ng VL, Mazariegos GV, Kelly B, Horslen S, McDiarmid SV, Magee JC, Loomes KM, Fischer RT, Sundaram SS, Lai JC, Te HS, Bucuvalas JC| | PubMed
  212. Nosocomial Infections Are Frequent and Negatively Impact Outcomes in Hospitalized Patients With Cirrhosis.
    Bajaj JS, O'Leary JG, Tandon P, Wong F, Garcia-Tsao G, Kamath PS, Biggins SW, Lai JC, Vargas HE, Maliakkal B, Fallon MB, Thuluvath PJ, Subramanian RM, Thacker LR, Reddy KR| | PubMed
  213. Impact of Muscle Gain after Transjugular Intrahepatic Portosystemic Shunt Creation on Patients Awaiting Liver Transplantation.
    Kohi MP, Lai JC| | PubMed
  214. Frailty in liver transplantation: An expert opinion statement from the American Society of Transplantation Liver and Intestinal Community of Practice.
    Lai JC, Sonnenday CJ, Tapper EB, Duarte-Rojo A, Dunn MA, Bernal W, Carey EJ, Dasarathy S, Kamath BM, Kappus MR, Montano-Loza AJ, Nagai S, Tandon P| | PubMed
  215. Changes in Simultaneous Liver-kidney Transplant Allocation Policy May Impact Postliver Transplant Outcomes.
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  216. Split-Liver Allocation: An Underused Opportunity to Expand Access to Liver Transplantation.
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  217. Targets to improve quality of care for patients with hepatic encephalopathy: data from a multi-centre cohort.
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  218. The Range and Reproducibility of the Liver Frailty Index.
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  219. Impact of Chronic Kidney Disease on Outcomes in Cirrhosis.
    Wong F, Reddy KR, O'Leary JG, Tandon P, Biggins SW, Garcia-Tsao G, Maliakkal BJ, Lai JC, Fallon MB, Vargas HE, Subramanian R, Thuluvath PJ, Kamath PS, Thacker L, Bajaj JS| | PubMed
  220. Outcomes in Patients With Cirrhosis on Primary Compared to Secondary Prophylaxis for Spontaneous Bacterial Peritonitis.
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  221. Outcomes After Listing for Liver Transplant in Patients With Acute-on-Chronic Liver Failure: The Multicenter North American Consortium for the Study of End-Stage Liver Disease Experience.
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  222. Women on the liver transplantation waitlist are at increased risk of hospitalization compared to men.
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  223. Deceased Pediatric Donor Livers: How Current Policy Drives Allocation and Transplantation.
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  224. Association Between Renal Function Pattern and Mortality in Patients With Cirrhosis.
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  225. Frailty Associated With Waitlist Mortality Independent of Ascites and Hepatic Encephalopathy in a Multicenter Study.
    Lai JC, Rahimi RS, Verna EC, Kappus MR, Dunn MA, McAdams-DeMarco M, Haugen CE, Volk ML, Duarte-Rojo A, Ganger DR, O'Leary JG, Dodge JL, Ladner D, Segev DL| | PubMed
  226. Functional status at listing predicts waitlist and posttransplant mortality in pediatric liver transplant candidates.
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  227. Report from the American Society of Transplantation on frailty in solid organ transplantation.
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  228. Sex hormone levels by presence and severity of cirrhosis in women with chronic hepatitis C virus infection.
    Sarkar M, Lai JC, Sawinski D, Zeigler TE, Cedars M, Forde KA| | PubMed
  229. How I Approach It: Improving Nutritional Status in Patients With Cirrhosis.
    Lai JC, Tandon P| | PubMed
  230. Poor performance of psoas muscle index for identification of patients with higher waitlist mortality risk in cirrhosis.
    Ebadi M, Wang CW, Lai JC, Dasarathy S, Kappus MR, Dunn MA, Carey EJ, Montano-Loza AJ, From the Fitness, Life Enhancement, and Exercise in Liver Transplantation (FLEXIT) Consortium| | PubMed
  231. Acute-on-Chronic Liver Failure: Getting Ready for Prime Time?
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  232. Beta-blockers and physical frailty in patients with end-stage liver disease.
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  233. Patient and Caregiver Attitudes and Practices of Exercise in Candidates Listed for Liver Transplantation.
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  234. Determination of Free 25(OH)D Concentrations and Their Relationships to Total 25(OH)D in Multiple Clinical Populations.
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  235. Association Between Intestinal Microbiota Collected at Hospital Admission and Outcomes of Patients With Cirrhosis.
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  236. People who experience seclusion in adult mental health inpatient services: An examination of health of the nation outcome scales scores.
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  237. "Normal" Creatinine Levels Predict Persistent Kidney Injury and Waitlist Mortality in Outpatients With Cirrhosis.
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  238. The Impact of Albumin Use on Resolution of Hyponatremia in Hospitalized Patients With Cirrhosis.
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  239. Receipt of a pediatric liver offer as the first offer reduces waitlist mortality for adult women.
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  240. Assessment of the spectrum of hepatic encephalopathy: A multicenter study.
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  241. Reply.
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  242. NACSELD acute-on-chronic liver failure (NACSELD-ACLF) score predicts 30-day survival in hospitalized patients with cirrhosis.
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  243. Physical frailty after liver transplantation.
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  244. Association of Cardiac Abnormalities to the Frail Phenotype in Cirrhotic Patients on the Waitlist: From the Functional Assessment in Liver Transplantation Study.
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  245. Primary healthcare utilisation among adults with mood and anxiety disorders: an analysis of the New Zealand Health Survey.
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  246. A2 liver transplantation across the ABO barrier: Increasing options in the donor pool?
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  247. Sex-based disparities in delisting for being "too sick" for liver transplantation.
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  248. Prediction of Fungal Infection Development and Their Impact on Survival Using the NACSELD Cohort.
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  249. The Liver Frailty Index Improves Mortality Prediction of the Subjective Clinician Assessment in Patients With Cirrhosis.
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  250. Opioid and opioid substitution therapy in liver transplant candidates: A survey of center policies and practices.
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  251. Liver Transplantation in the Obese Cirrhotic Patient.
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  252. Transplant for the very sick: No limitations in donor quality?
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  253. Analysis of Liver Offers to Pediatric Candidates on the Transplant Wait List.
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  254. Development of a novel frailty index to predict mortality in patients with end-stage liver disease.
    Lai JC, Covinsky KE, Dodge JL, Boscardin WJ, Segev DL, Roberts JP, Feng S| | PubMed
  255. Race/ethnicity is associated with ABO-nonidentical liver transplantation in the United States.
    Ge J, Roberts JP, Lai JC| | PubMed
  256. Reporting functional status in UNOS: The weakness of the Karnofsky Performance Status Scale.
    Wang CW, Lai JC| | PubMed
  257. A multicenter study to define sarcopenia in patients with end-stage liver disease.
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  258. Cost-Effectiveness of Direct-Acting Antiviral Treatment in Hepatitis C-Infected Liver Transplant Candidates With Compensated Cirrhosis and Hepatocellular Carcinoma.
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  259. Disability in patients with end-stage liver disease: Results from the functional assessment in liver transplantation study.
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  260. Frailty is independently associated with increased hospitalisation days in patients on the liver transplant waitlist.
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  261. A framework to determine when liver transplantation is futile.
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  262. Clinical Liver Disease
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  264. Factors Associated with Medication Non-adherence in Patients with End-Stage Liver Disease.
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  265. Editorial: Advancing Adoption of Frailty to Improve the Care of Patients with Cirrhosis: Time for a Consensus on a Frailty Index.
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  266. Performance-Based Measures Associate With Frailty in Patients With End-Stage Liver Disease.
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  267. Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy.
    Giard JM, Decker KA, Lai JC, Gill RM, Logan AC, Fix OK| | PubMed
  268. Hepatic Encephalopathy Is Associated With Mortality in Patients With Cirrhosis Independent of Other Extrahepatic Organ Failures.
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  269. Underutilization of palliative care services in the liver transplant population.
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  270. A Comparison of Muscle Function, Mass, and Quality in Liver Transplant Candidates: Results From the Functional Assessment in Liver Transplantation Study.
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  271. ABO-Nonidentical Liver Transplantation in the United States.
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  272. Defining the threshold for too sick for transplant.
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  273. Response to clinical assessments of health status as a potential marker to identify patients who are too sick to undergo transplantation.
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  274. Functional decline in patients with cirrhosis awaiting liver transplantation: Results from the functional assessment in liver transplantation (FrAILT) study.
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  275. Functional impairment in older liver transplantation candidates: From the functional assessment in liver transplantation study.
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  276. Outcomes for liver transplant candidates listed with low model for end-stage liver disease score.
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  277. Kidney Failure and Liver Allocation: Current Practices and Potential Improvements.
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  278. Decision support for organ offers in liver transplantation.
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  279. Hepatitis C genotype influences post-liver transplant outcomes.
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  280. Total 25(OH) vitamin D, free 25(OH) vitamin D and markers of bone turnover in cirrhotics with and without synthetic dysfunction.
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  281. Clinician assessments of health status predict mortality in patients with end-stage liver disease awaiting liver transplantation.
    Lai JC, Covinsky KE, Hayssen H, Lizaola B, Dodge JL, Roberts JP, Terrault NA, Feng S| | PubMed
  282. Bone Mineral Density, Bone Turnover, and Systemic Inflammation in Non-cirrhotics with Chronic Hepatitis C.
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  283. Role of delta-aminolevulinic acid in the symptoms of acute porphyria.
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  284. Combined effects of recipient age and model for end-stage liver disease score on liver transplantation outcomes.
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  285. The octogenarian donor: can the liver be "younger than stated age"?
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  286. Expanded criteria donors.
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  287. Frailty predicts waitlist mortality in liver transplant candidates.
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  288. A comparison of measured and calculated free 25(OH) vitamin D levels in clinical populations.
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  289. Variability in free 25(OH) vitamin D levels in clinical populations.
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  290. Reducing infection transmission in solid organ transplantation through donor nucleic acid testing: a cost-effectiveness analysis.
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  291. Offer patterns of nationally placed livers by donation service area.
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  292. Center competition and outcomes following liver transplantation.
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  293. Sudden onset vision loss in an 8-year-old female with McCune-Albright syndrome.
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  294. An examination of liver offers to candidates on the liver transplant wait-list.
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  295. Recipient-donor race mismatch for African American liver transplant patients with chronic hepatitis C.
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  296. Risk of advanced fibrosis with grafts from hepatitis C antibody-positive donors: a multicenter cohort study.
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  297. Effects of ethnicity and socioeconomic status on survival and severity of fibrosis in liver transplant recipients with hepatitis C virus.
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  298. Patient, center and geographic characteristics of nationally placed livers.
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  299. Hepatic steatosis at 1 year is an additional predictor of subsequent fibrosis severity in liver transplant recipients with recurrent hepatitis C virus.
    Brandman D, Pingitore A, Lai JC, Roberts JP, Ferrell L, Bass NM, Terrault NA| | PubMed
  300. Hepatitis C virus-infected women have a higher risk of advanced fibrosis and graft loss after liver transplantation than men.
    Lai JC, Verna EC, Brown RS, O'Leary JG, Trotter JF, Forman LM, Duman JD, Foster RG, Stravitz RT, Terrault NA, Consortium to Study Health Outcomes in HCV Liver Transplant Recipients (CRUSH-C)| | PubMed
  301. Gender differences in liver donor quality are predictive of graft loss.
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  302. Height contributes to the gender difference in wait-list mortality under the MELD-based liver allocation system.
    Lai JC, Terrault NA, Vittinghoff E, Biggins SW| | PubMed
  303. Lessons from HIV therapy applied to viral hepatitis therapy: summary of a workshop.
    Monto A, Schooley RT, Lai JC, Sulkowski MS, Chung RT, Pawlotsky JM, McHutchison JG, Jacobson IM| | PubMed
  304. A novel housestaff educational model for quaternary-care patients at an academic health center.
    Lai JC, Montero A, Lebwohl B, Brown RS| | PubMed
  305. Resource utilization of living donor versus deceased donor liver transplantation is similar at an experienced transplant center.
    Lai JC, Pichardo EM, Emond JC, Brown RS| | PubMed