Biography
She has worked at UCSF to develop interdisciplinary teams of clinicians and researchers to bring the best care to patients and find the best platform to integrate translational research and improve the delivery of breast cancer care. In 2005, she received the NCI SPORE Investigator of the Year Award, an internationally recognized honor and designation.
She is the Principal Investigator of the I-SPY TRIAL program, a multi-site neoadjuvant clinical trial that has evolved into a model for translational research and innovation in clinical trial design.
Dr. Esserman launched a University of California-wide breast cancer initiative called the Athena Breast Health Network, a project designed to follow 400,000 women from screening through treatment and outcomes, incorporating the latest in molecular testing and web-based tools into the course of care.
Dr. Esserman is nationally and internationally known as a leader in the field of breast cancer and has published over 200 articles in peer-reviewed journals covering all aspects of breast health including information systems, immunology, decision making, health policy and the use of imaging. She speaks extensively at public and private forums within the U.S. and internationally. Overall, Dr. Esserman's research and writing tends to focus on the goal of giving patients better access to accurate information so that they can become partners in their health care.
She was a member of President Obama’s Council of Advisors on Science and Technology (PCAST) Working Group on Advancing Innovation in Drug Development and Evaluation, which studied how the federal government can best support science-based innovation in the process of drug development and regulatory evaluation. In addition, she was a contributing member of a “taskforce” for President Obama’s Council of Advisors on Science and Technology.
Dr. Esserman received her Bachelor's degree in History of Science from Harvard University and completed her M.D. at Stanford University. She completed her surgery residency and oncology fellowship at Stanford University Medical Center. After her training, she joined the faculty at Stanford and received a Hartford fellowship to attend Stanford Business School where she received her M.B.A. in 1993. She then joined the faculty at the University of California, San Francisco.
Education
1974-77, Harvard University, A.B.
1978-83, Stanford University, M.D.
1983-85, Stanford University School of Medicine, Resident, General Surgery
1988-90, Stanford University School of Medicine, Resident, General Surgery
1990-91, Stanford University School of Medicine, Chief Resident, General Surgery
1985-88, Stanford University School of Medicine, Postdoctoral Fe, Oncology, Medical
1991-93, Stanford University, M.B.A.
Board Certifications
American Board of Surgery - General Surgery - 1992
Collaboration Interests
I am interested in:
- policy change
Clinical Expertise
DCIS (Ductal Carcinoma in situ)
Inflammatory Breast Cancer
Invasive Breast Cancer
LCIS (Lobular Carcinoma in situ)
Lumpectomy/Partial Mastectomy
Lymphadenectomy
Mastectomy
Recurrent Breast Cancer
Sentinel Lymph Node Biopsy
Wire Localization Surgery
Clinical Trials
- MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles (NCT03053193)Related Conditions: Breast Cancer| Start Date: | End Date:
- DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment (NCT06075953)Related Conditions: Ductal Carcinoma in Situ, Breast Cancer, Carcinoma| Start Date: | End Date:
- Related Conditions: COVID-19| Start Date: | End Date:
- Related Conditions: Breast Cancer, Menopause| Start Date: | End Date:
- Related Conditions: Breast Cancer, Cancer, General| Start Date: | End Date:
- Related Conditions: Carcinoma, Intraductal, Noninfiltrating, Immunotherapy, Carcinoma| Start Date: | End Date:
- Related Conditions: Breast Cancer, Carcinoma| Start Date: | End Date:
- Diagnostic Procedures in Women With Locally Advanced Breast Cancer Who Are Receiving Chemotherapy Before Breast Cancer Surgery (NCT00033397)Related Conditions: Breast Cancer| Start Date: | End Date:
- Effect of Fluvastatin on Biomarkers in Women Who Are Undergoing Surgery for Ductal Carcinoma In Situ or Stage I Breast Cancer (NCT00416403)Related Conditions: Breast Cancer, Carcinoma| Start Date: | End Date:
- Postoperative Pain Control With Fentanyl Patch in Patients Undergoing Mastectomy and TRAM or DIEP Flap Reconstruction (NCT01258296)Related Conditions: Postoperative Pain| Start Date: | End Date:
- Related Conditions: Breast Cancer| Start Date: | End Date:
- Statins and Breast Cancer Biomarkers (NCT00914017)Related Conditions: Breast Cancer| Start Date:
Program Affiliations
- UCSF Center of Excellence for Breast Cancer Care
- UCSF Breast Care Center
- UCSF Helen Diller Comprehensive Cancer Center
Translational Co-Lead: Dr. Laura Esserman, is internationally recognized for her leadership of the ground-breaking I-SPY2 clinical trial and as an advocate for de-escalation of treatment for DCIS, and the initiation of the virtual preference pragmatic personalized screening trial (WISDOM) seeking to personalize the approach to screening. Her work in breast cancer spans the spectrum from public policy issues to basic science and the impact of both on the delivery of clinical care. Dr. Esserman has mentored 36 post-doctoral or clinical fellows during her career. She developed and runs a post-baccalaureate program that has trained 123 students over the past 15 years, most of whom have gone on to careers in medicine.
Dr. Esserman’s broad research interests provide exceptional opportunities for multidisciplinary training across the three themes, through clinical trials and biomarker studies on screening, prevention and treatment of breast cancer, many of which focus on improving healthcare value. Another fundamental and scalable effort is the implementation of systems to integrate care and research.
In the News
Grants and Funding
- Surgical Oncology Training Grant | NIH | 2020-07-15 - 2025-06-30 | Role: Principal Investigator
- Extending the Diversity, Reach, and Generalizability of the WISDOM Study | NIH | 2020-03-01 - 2025-02-28 | Role: Principal Investigator
- I-SPY2 +: Evolving the I-SPY 2 TRIAL to include MRI-directed, adaptive sequential treatment to optimize breast cancer outcomes | NIH | 2017-09-08 - 2022-08-31 | Role: Principal Investigator
- Elucidating the molecular and contextual basis for IDLE ultralow risk lesions and the tumor immune microenvironment of high risk in situ and invasive breast cancers | NIH | 2015-09-16 - 2021-08-31 | Role: Principal Investigator
- Modeling the Impact of Targeted Therapy Based on Breast Cancer Subtypes | NIH | 2014-09-18 - 2020-08-31 | Role: Principal Investigator
- Integrated Biomarkers to Characterize Breast Cancer Risk | NIH | 2004-09-20 - 2011-06-30 | Role: Principal Investigator
Research Interests
- BRCA1 Protein
- BRCA2 Protein
- Breast Diseases
- Breast Neoplasms
- Male
- Mastectomy
- Segmental
- Ultrasonography
- Mammary
- Cancer Vaccines
- Genes
- Tumor Suppressor
- Oncogenes
- Precancerous Conditions
- Infiltrating Duct Carcinoma
- Intraductal Carcinoma
- Noninfiltrating Carcinoma Lobular
Publications
- Correction: A roadmap to reduce the incidence and mortality of breast cancer by rethinking our approach to women's health.| | PubMed
- Bilateral Mastectomy vs Lumpectomy and Breast Cancer Mortality Risk.| | PubMed
- Differential long-term tamoxifen therapy benefit by menopausal status in breast cancer patients: secondary analysis of a controlled randomized clinical trial.| | PubMed
- Impact of IVF Restriction on Patients With Cancer and Surgeons.| | PubMed
- Pexidartinib and standard neoadjuvant therapy in the adaptively randomized I-SPY2 trial for early breast cancer.| | PubMed
- Relationship Between Perceived COVID-19 Risk and Change in Perceived Breast Cancer Risk: Prospective Observational Study.| | PubMed
- Tumor Morphology for Prediction of Poor Responses Early in Neoadjuvant Chemotherapy for Breast Cancer: A Multicenter Retrospective Study.| | PubMed
- Hormone Receptor Positive HER2-negative/MammaPrint High-2 Breast Cancers Closely Resemble Triple Negative Breast Cancers.| | PubMed
- A roadmap to reduce the incidence and mortality of breast cancer by rethinking our approach to women's health.| | PubMed
- Balancing risks of surgical complications and positive margins for patients with invasive lobular carcinoma of the breast and elevated BMI: An institutional cohort study.| | PubMed
- Multi-platform biomarkers of response to an immune checkpoint inhibitor in the neoadjuvant I-SPY 2 trial for early-stage breast cancer.| | PubMed
- Screening Mammography for 40-Year-Old Women-Whose Decision?| | PubMed
- Gut and oral microbial compositional differences in women with breast cancer, women with ductal carcinoma in situ, and healthy women.| | PubMed
- Pathologic complete response (pCR) rates for patients with HR+/HER2- high-risk, early-stage breast cancer (EBC) by clinical and molecular features in the phase II I-SPY2 clinical trial.| | PubMed
- Validation study of risk-reduction activities after personalized breast cancer education tool in the WISDOM study.| | PubMed
- Regional lymph node changes on breast MRI in patients with early-stage breast cancer receiving neoadjuvant chemo-immunotherapy.| | PubMed
- Overcoming challenges in conducting early phase breast cancer prevention trials: Bazedoxifene and conjugated estrogens vs waitlist control.| | PubMed
- Datopotamab-deruxtecan in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial.| | PubMed
- Datopotamab-deruxtecan plus durvalumab in early-stage breast cancer: the sequential multiple assignment randomized I-SPY2.2 phase 2 trial.| | PubMed
- Implementation and impact of an electronic patient reported outcomes system in a phase II multi-site adaptive platform clinical trial for early-stage breast cancer.| | PubMed
- Modernizing the Data Infrastructure for Clinical Research to Meet Evolving Demands for Evidence.| | PubMed
- Magnetic resonance imaging insights from active surveillance of women with ductal carcinoma in situ.| | PubMed
- Clipping the Positive Lymph Node in Patients with Clinically Node Positive Breast Cancer Treated with Neoadjuvant Chemotherapy: Impact on Axillary Surgery in the ISPY-2 Clinical Trial.| | PubMed
- Internal Mammary Lymphadenopathy Does Not Impact Oncologic Outcomes in Patients Treated with Neoadjuvant Chemotherapy: Results from the I-SPY2 Clinical Trial.| | PubMed
- Cell-free DNA Concentration as a Biomarker of Response and Recurrence in HER2-Negative Breast Cancer Receiving Neoadjuvant Chemotherapy.| | PubMed
- Tumor microenvironmental determinants of high-risk DCIS progression.| | PubMed
- Reproductive rights in the United States: acquiescence is not a strategy.| | PubMed
- Epithelial Expressed B7-H4 Drives Differential Immunotherapy Response in Murine and Human Breast Cancer.| | PubMed
- Neoadjuvant Chemotherapy and Immunotherapy for Estrogen Receptor-Positive Human Epidermal Growth Factor 2-Negative Breast Cancer.| | PubMed
- RE: Supplemental magnetic resonance imaging plus mammography compared with magnetic resonance imaging or mammography by extent of breast density.| | PubMed
- Incidence and Mitigation of Corneal Pseudomicrocysts Induced by Antibody-Drug Conjugates (ADCs).| | PubMed
- Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers.| | PubMed
- 18F-FDG Dedicated Breast PET Complementary to Breast MRI for Evaluating Early Response to Neoadjuvant Chemotherapy.| | PubMed
- Circulating tumor cells in early lobular versus ductal breast cancer and their associations with prognosis.| | PubMed
- Novel subtypes of severe COVID-19 respiratory failure based on biological heterogeneity: a secondary analysis of a randomized controlled trial.| | PubMed
- Neoadjuvant Trebananib plus Paclitaxel-based Chemotherapy for Stage II/III Breast Cancer in the Adaptively Randomized I-SPY2 Trial-Efficacy and Biomarker Discovery.| | PubMed
- Duration of Endocrine Treatment for DCIS impacts second events: Insights from a large cohort of cases at two academic medical centers.| | PubMed
- Characterizing attitudes related to future child-bearing in young women diagnosed with early-stage breast cancer.| | PubMed
- Precision Oncology in Breast Cancer Surgery.| | PubMed
- Protein signaling and drug target activation signatures to guide therapy prioritization: Therapeutic resistance and sensitivity in the I-SPY 2 Trial.| | PubMed
- Race, Gene Expression Signatures, and Clinical Outcomes of Patients With High-Risk Early Breast Cancer.| | PubMed
- Concordance between patient-reported and physician-documented comorbidities and symptoms among Stage 4 breast cancer patients.| | PubMed
- The impact of histologic subtype on primary site surgery in the management of metastatic lobular versus ductal breast cancer: a population based study from the National Cancer Database (NCDB).| | PubMed
- Pituitary adenoma or neuroendocrine tumour: the need for an integrated prognostic classification.| | PubMed
- Area Deprivation Index in Patients with Invasive Lobular Carcinoma of the Breast: Associations with Tumor Characteristics and Outcomes.| | PubMed
- Early Ascertainment of Breast Cancer Diagnoses Comparing Self-Reported Questionnaires and Electronic Health Record Data Warehouse: The WISDOM Study.| | PubMed
- The impact of histologic subtype on primary site surgery in the management of metastatic lobular versus ductal breast cancer: a population based study from the National Cancer Database.| | PubMed
- Predictors of Early Versus Late Recurrence in Invasive Lobular Carcinoma of the Breast: Impact of Local and Systemic Therapy.| | PubMed
- Effect of Longitudinal Variation in Tumor Volume Estimation for MRI-guided Personalization of Breast Cancer Neoadjuvant Treatment.| | PubMed
- A Truly Pro-Life Position Requires Access to Reproductive Health Care.| | PubMed
- Changes in Surgical Management of the Axilla Over 11 Years - Report on More Than 1500 Breast Cancer Patients Treated with Neoadjuvant Chemotherapy on the Prospective I-SPY2 Trial.| | PubMed
- Breast Conservation Surgery and Mastectomy Have Similar Locoregional Recurrence After Neoadjuvant Chemotherapy: Results From 1462 Patients on the Prospective, Randomized I-SPY2 Trial.| | PubMed
- Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes.| | PubMed
- Comparison of Mammography AI Algorithms with a Clinical Risk Model for 5-year Breast Cancer Risk Prediction: An Observational Study.| | PubMed
- Prognostic Significance of Residual Ductal Carcinoma In Situ After Complete Response of Invasive Breast Cancer to Neoadjuvant Therapy-Reply.| | PubMed
- Development and testing of a polygenic risk score for breast cancer aggressiveness.| | PubMed
- Validation Study on Risk-Reduction Activities after Exposure to a Personalized Breast Cancer Risk-Assessment Education Tool in High-Risk Women in the WISDOM Study.| | PubMed
- Clinical significance and biology of circulating tumor DNA in high-risk early-stage HER2-negative breast cancer receiving neoadjuvant chemotherapy.| | PubMed
- Time to Surgery in Breast Cancer-Is Faster Always Better?| | PubMed
- Association of baseline ROR1 and ROR2 gene expression with clinical outcomes in the I-SPY2 neoadjuvant breast cancer trial.| | PubMed
- Guiding principles for the responsible development of artificial intelligence tools for healthcare.| | PubMed
- Radiomic tumor phenotypes augment molecular profiling in predicting recurrence free survival after breast neoadjuvant chemotherapy.| | PubMed
- Implantation of engineered adipocytes that outcompete tumors for resources suppresses cancer progression.| | PubMed
- When Less Can Be More: How the 10-Year Updated Results From the Randomized Controlled AMAROS Trial Should Affect Axillary Management in the Setting of a Positive Node.| | PubMed
- Expanding Candidacy for Nipple-sparing Mastectomy in Women with Large or Ptotic Breasts: Staged Reconstruction Outcomes.| | PubMed
- Outcomes and clinicopathologic characteristics associated with disseminated tumor cells in bone marrow after neoadjuvant chemotherapy in high-risk early stage breast cancer: the I-SPY SURMOUNT study.| | PubMed
- Identifying Good Candidates for Active Surveillance of Ductal Carcinoma In Situ: Insights from a Large Neoadjuvant Endocrine Therapy Cohort.| | PubMed
- Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer.| | PubMed
- Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.| | PubMed
- Association of Residual Ductal Carcinoma In Situ With Breast Cancer Recurrence in the Neoadjuvant I-SPY2 Trial.| | PubMed
- Informed consent process in the ISPY COVID trial is ethically acceptable.| | PubMed
- Focal Therapy for Prostate Cancer: Evolutionary Parallels to Breast Cancer Treatment.| | PubMed
- Diffusion-Weighted MRI for Predicting Pathologic Complete Response in Neoadjuvant Immunotherapy.| | PubMed
- Twenty-Year Benefit From Adjuvant Goserelin and Tamoxifen in Premenopausal Patients With Breast Cancer in a Controlled Randomized Clinical Trial.| | PubMed
- Validation of the 70-gene signature test (MammaPrint) to identify patients with breast cancer aged ≥ 70 years with ultralow risk of distant recurrence: A population-based cohort study.| | PubMed
- Why It Is Time to Challenge Entrenched Beliefs About Breast Cancer Screening.| | PubMed
- Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.| | PubMed
- Optimizing hormone therapy for breast cancer: Translating gains to the early-stage setting.| | PubMed
- I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations.| | PubMed
- Redefining breast cancer subtypes to guide treatment prioritization and maximize response: Predictive biomarkers across 10 cancer therapies.| | PubMed
- Treatment Efficacy Score-continuous residual cancer burden-based metric to compare neoadjuvant chemotherapy efficacy between randomized trial arms in breast cancer trials.| | PubMed
- Effect of Inter-Reader Variability on Diffusion-Weighted MRI Apparent Diffusion Coefficient Measurements and Prediction of Pathologic Complete Response for Breast Cancer.| | PubMed
- Association of Residual Cancer Burden After Neoadjuvant Therapy and Event-Free Survival in Breast Cancer-Reply.| | PubMed
- Clinical and molecular characteristics of estrogen receptor-positive ultralow risk breast cancer tumors identified by the 70-gene signature.| | PubMed
- Survivorship after neoadjuvant chemotherapy - Authors' reply.| | PubMed
- Evaluation of the Pathways for Survivors Program to Address Breast Cancer Survivorship-Associated Distress: Survey Study.| | PubMed
- Outcome of Patients With an Ultralow-Risk 70-Gene Signature in the MINDACT Trial.| | PubMed
- The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ.| | PubMed
- The incidence of discordant clinical and genomic risk in patients with invasive lobular or ductal carcinoma of the breast: a National Cancer Database Study.| | PubMed
- Residual cancer burden after neoadjuvant chemotherapy and long-term survival outcomes in breast cancer: a multicentre pooled analysis of 5161 patients.| | PubMed
- A case-case analysis of women with breast cancer: predictors of interval vs screen-detected cancer.| | PubMed
- Neoadjuvant T-DM1/pertuzumab and paclitaxel/trastuzumab/pertuzumab for HER2+ breast cancer in the adaptively randomized I-SPY2 trial.| | PubMed
- RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer.| | PubMed
- Assessment of Residual Cancer Burden and Event-Free Survival in Neoadjuvant Treatment for High-risk Breast Cancer: An Analysis of Data From the I-SPY2 Randomized Clinical Trial.| | PubMed
- Decreased enrollment in breast cancer trials by histologic subtype: does invasive lobular carcinoma resist RECIST?| | PubMed
- Ganitumab and metformin plus standard neoadjuvant therapy in stage 2/3 breast cancer.| | PubMed
- Pre-Appointment Nurse Navigation: Patient-Centered Findings From a Survey of Patients With Breast Cancer.| | PubMed
- Health screening needs independent regular re-evaluation.| | PubMed
- Trigger point injection for post-mastectomy pain: a simple intervention with high rate of long-term relief.| | PubMed
- The WISDOM study: a new approach to screening can and should be tested.| | PubMed
- The use of neoadjuvant therapy to further personalize breast cancer treatment.| | PubMed
- Breast MRI during Neoadjuvant Chemotherapy: Lack of Background Parenchymal Enhancement Suppression and Inferior Treatment Response.| | PubMed
- Elevated risk thresholds predict endocrine risk-reducing medication use in the Athena screening registry.| | PubMed
- Authors' Reply: To the Letter to the Editor by Groheux et al.| | PubMed
- Advancing precision medicine for acute respiratory distress syndrome.| | PubMed
- Development and pilot of an online, personalized risk assessment tool for a breast cancer precision medicine trial.| | PubMed
- Durvalumab with olaparib and paclitaxel for high-risk HER2-negative stage II/III breast cancer: Results from the adaptively randomized I-SPY2 trial.| | PubMed
- Positive margins after mastectomy in patients with invasive lobular carcinoma of the breast: Incidence and management strategies.| | PubMed
- PRoBE the cloud toolkit: finding the best biomarkers of drug response within a breast cancer clinical trial.| | PubMed
- Assessment of 25-Year Survival of Women With Estrogen Receptor-Positive/ERBB2-Negative Breast Cancer Treated With and Without Tamoxifen Therapy: A Secondary Analysis of Data From the Stockholm Tamoxifen Randomized Clinical Trial.| | PubMed
- Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection.| | PubMed
- Incorporation of Patient-Reported Outcomes Measurement Information System to assess quality of life among patients with breast cancer initiating care at an academic center.| | PubMed
- Mask-Guided Convolutional Neural Network for Breast Tumor Prognostic Outcome Prediction on 3D DCE-MR Images.| | PubMed
- Circulating tumor DNA and magnetic resonance imaging to predict neoadjuvant chemotherapy response and recurrence risk.| | PubMed
- Accuracy of breast MRI in evaluating nodal status after neoadjuvant therapy in invasive lobular carcinoma.| | PubMed
- Predicted sensitivity to endocrine therapy for stage II-III hormone receptor-positive and HER2-negative (HR+/HER2-) breast cancer before chemo-endocrine therapy.| | PubMed
- Characterizing the Tumor Immune Microenvironment with Tyramide-Based Multiplex Immunofluorescence.| | PubMed
- Contralateral prophylactic mastectomy: A narrative review of the evidence and acceptability.| | PubMed
- A world-wide survey on kidney transplantation practices in breast cancer survivors: The need for new management guidelines.| | PubMed
- Characterization of Oligometastatic Disease in a Real-World Nationwide Cohort of 3447 Patients With de Novo Metastatic Breast Cancer.| | PubMed
- Accuracy of sentinel lymph node biopsy in invasive lobular carcinoma of the breast: Factors associated with false negatives.| | PubMed
- MCM3 upregulation confers endocrine resistance in breast cancer and is a predictive marker of diminished tamoxifen benefit.| | PubMed
- Prime Time for Consultation Audio Recordings: Supporting Shared Decision Making During and After the COVID-19 Era.| | PubMed
- Evaluation of primary breast cancers using dedicated breast PET and whole-body PET.| | PubMed
- Predicting breast cancer response to neoadjuvant treatment using multi-feature MRI: results from the I-SPY 2 TRIAL.| | PubMed
- Circulating tumor DNA in neoadjuvant-treated breast cancer reflects response and survival.| | PubMed
- Mutational profiling of micro-dissected pre-malignant lesions from archived specimens.| | PubMed
- Use of 18F-FDG PET/CT as an Initial Staging Procedure for Stage II-III Breast Cancer: A Multicenter Value Analysis.| | PubMed
- Publisher Correction: Personalized early detection and prevention of breast cancer: ENVISION consensus statement.| | PubMed
- The quality of life index: a pilot study integrating treatment efficacy and quality of life in oncology.| | PubMed
- The Evolution of Our Understanding of the Biology of Cancer Is the Key to Avoiding Overdiagnosis and Overtreatment.| | PubMed
- Oncological Outcomes of Total Skin-Sparing Mastectomy for Invasive Lobular Carcinoma of the Breast: A 20-Year Institutional Experience.| | PubMed
- Mechanism of action biomarkers predicting response to AKT inhibition in the I-SPY 2 breast cancer trial.| | PubMed
- Association of Event-Free and Distant Recurrence-Free Survival With Individual-Level Pathologic Complete Response in Neoadjuvant Treatment of Stages 2 and 3 Breast Cancer: Three-Year Follow-up Analysis for the I-SPY2 Adaptively Randomized Clinical Trial.| | PubMed
- Cost-effectiveness of consensus guideline based management of pancreatic cysts: The sensitivity and specificity required for guidelines to be cost-effective.| | PubMed
- Predictive Value of Breast MRI Background Parenchymal Enhancement for Neoadjuvant Treatment Response among HER2- Patients.| | PubMed
- Evaluating the impact of axillary dissection on recurrence-free survival by extent of nodal disease in invasive lobular carcinoma of the breast.| | PubMed
- Breast conservation therapy versus mastectomy in the surgical management of invasive lobular carcinoma measuring 4 cm or greater.| | PubMed
- Personalized early detection and prevention of breast cancer: ENVISION consensus statement.| | PubMed
- Current Landscape of Breast Cancer Imaging and Potential Quantitative Imaging Markers of Response in ER-Positive Breast Cancers Treated with Neoadjuvant Therapy.| | PubMed
- Comparison of Segmentation Methods in Assessing Background Parenchymal Enhancement as a Biomarker for Response to Neoadjuvant Therapy.| | PubMed
- Impact of MRI Protocol Adherence on Prediction of Pathological Complete Response in the I-SPY 2 Neoadjuvant Breast Cancer Trial.| | PubMed
- Tumor Sphericity Predicts Response in Neoadjuvant Chemotherapy for Invasive Breast Cancer.| | PubMed
- Effect of Pembrolizumab Plus Neoadjuvant Chemotherapy on Pathologic Complete Response in Women With Early-Stage Breast Cancer: An Analysis of the Ongoing Phase 2 Adaptively Randomized I-SPY2 Trial.| | PubMed
- Personalization of Treatment is the Way Forward in Care and Trials.| | PubMed
- Mitotic score and pleomorphic histology in invasive lobular carcinoma of the breast: impact on disease-free survival.| | PubMed
- Response to Carter et al.| | PubMed
- Phase II Single-Arm Study of Preoperative Letrozole for Estrogen Receptor-Positive Postmenopausal Ductal Carcinoma In Situ: CALGB 40903 (Alliance).| | PubMed
- We need more evidence to answer questions about screening.| | PubMed
- Abdominal Imaging of Pancreatic Cysts and Cyst-Associated Pancreatic Cancer in BRCA1/2 Mutation Carriers: A Retrospective Cross-Sectional Study.| | PubMed
- Success rates of re-excision after positive margins for invasive lobular carcinoma of the breast.| | PubMed
- Assessment of Long-term Distant Recurrence-Free Survival Associated With Tamoxifen Therapy in Postmenopausal Patients With Luminal A or Luminal B Breast Cancer.| | PubMed
- A case report of vanishing bile duct syndrome after exposure to pexidartinib (PLX3397) and paclitaxel.| | PubMed
- Synchronous Detection of Circulating Tumor Cells in Blood and Disseminated Tumor Cells in Bone Marrow Predicts Adverse Outcome in Early Breast Cancer.| | PubMed
- Fitbit Usage in Patients With Breast Cancer Undergoing Chemotherapy.| | PubMed
- Additive value of diffusion-weighted MRI in the I-SPY 2 TRIAL.| | PubMed
- Initial experience of dedicated breast PET imaging of ER+ breast cancers using [F-18]fluoroestradiol.| | PubMed
- A response to "Personalised medicine and population health: breast and ovarian cancer".| | PubMed
- MK-2206 and Standard Neoadjuvant Chemotherapy Improves Response in Patients With Human Epidermal Growth Factor Receptor 2-Positive and/or Hormone Receptor-Negative Breast Cancers in the I-SPY 2 Trial.| | PubMed
- Should we rename low risk cancers?| | PubMed
- Evaluation of National Comprehensive Cancer Network guideline-based Tool for Risk Assessment for breast and ovarian Cancer (N-TRAC): A patient-reported survey for genetic high-risk assessment for breast and ovarian cancers in women.| | PubMed
- The WISDOM Personalized Breast Cancer Screening Trial: Simulation Study to Assess Potential Bias and Analytic Approaches.| | PubMed
- Erratum: Author Correction: Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint.| | PubMed
- Functional Status and Survival After Breast Cancer Surgery in Nursing Home Residents.| | PubMed
- Precision risk-based screening might maximize benefit and minimize harm.| | PubMed
- Test-retest repeatability and reproducibility of ADC measures by breast DWI: Results from the ACRIN 6698 trial.| | PubMed
- Genomic and expression profiling reveal molecular heterogeneity of disseminated tumor cells in bone marrow of early breast cancer.| | PubMed
- Diffusion-weighted MRI Findings Predict Pathologic Response in Neoadjuvant Treatment of Breast Cancer: The ACRIN 6698 Multicenter Trial.| | PubMed
- Surgical Standards for Management of the Axilla in Breast Cancer Clinical Trials with Pathological Complete Response Endpoint.| | PubMed
- Evaluation of the HER/PI3K/AKT Family Signaling Network as a Predictive Biomarker of Pathologic Complete Response for Patients With Breast Cancer Treated With Neratinib in the I-SPY 2 TRIAL.| | PubMed
- Exploration of PET and MRI radiomic features for decoding breast cancer phenotypes and prognosis.| | PubMed
- Breast Conservation and Negative Margins in Invasive Lobular Carcinoma: The Impact of Oncoplastic Surgery and Shave Margins in 358 Patients.| | PubMed
- The DigniCap Scalp Cooling System and its use in the treatment of chemotherapy-induced alopecia.| | PubMed
- Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer.| | PubMed
- Circulating Tumor Cells in Breast Cancer Patients Treated by Neoadjuvant Chemotherapy: A Meta-analysis.| | PubMed
- Systematic review of the impact of breast-conserving surgery on cancer outcomes of multiple ipsilateral breast cancers.| | PubMed
- MRI, Clinical Examination, and Mammography for Preoperative Assessment of Residual Disease and Pathologic Complete Response After Neoadjuvant Chemotherapy for Breast Cancer: ACRIN 6657 Trial.| | PubMed
- Improved analgesia and reduced post-operative nausea and vomiting after implementation of an enhanced recovery after surgery (ERAS) pathway for total mastectomy.| | PubMed
- Initial Clinical Experience With an Inducible Magnetic Seed System for Preoperative Breast Lesion Localization.| | PubMed
- Complications After Total Skin-Sparing Mastectomy and Expander-Implant Reconstruction: Effects of Radiation Therapy on the Stages of Reconstruction.| | PubMed
- Features of MRI stromal enhancement with neoadjuvant chemotherapy: a subgroup analysis of the ACRIN 6657/I-SPY TRIAL.| | PubMed
- Rapid detection of BRCA1/2 recurrent mutations in Chinese breast and ovarian cancer patients with multiplex SNaPshot genotyping panels.| | PubMed
- Mechanisms of Resistance to Neoadjuvant Chemotherapy in Breast Cancer.| | PubMed
- Use of Molecular Tools to Identify Patients With Indolent Breast Cancers With Ultralow Risk Over 2 Decades.| | PubMed
- The value of embedding: integrated palliative care for patients with metastatic breast cancer.| | PubMed
- Registry study to assess hair loss prevention with the Penguin Cold Cap in breast cancer patients receiving chemotherapy.| | PubMed
- The WISDOM Study: breaking the deadlock in the breast cancer screening debate.| | PubMed
- Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors.| | PubMed
- DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial.| | PubMed
- Tamoxifen therapy benefit for patients with 70-gene signature high and low risk.| | PubMed
- Erratum to: Fertility preservation with ovarian stimulation and time to treatment in women with stage II-III breast cancer receiving neoadjuvant therapy.| | PubMed
- Indications for Postmastectomy Radiation After Neoadjuvant Chemotherapy in ypN0 and ypN1-3 Axillary Node-Positive Women.| | PubMed
- Comparison of residual cancer burden, American Joint Committee on Cancer staging and pathologic complete response in breast cancer after neoadjuvant chemotherapy: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).| | PubMed
- Receptor activator of nuclear factor kappa B (RANK) expression in primary breast cancer correlates with recurrence-free survival and development of bone metastases in I-SPY1 (CALGB 150007/150012; ACRIN 6657).| | PubMed
- Fertility preservation with ovarian stimulation and time to treatment in women with stage II-III breast cancer receiving neoadjuvant therapy.| | PubMed
- Vaginal Testosterone Cream vs Estradiol Vaginal Ring for Vaginal Dryness or Decreased Libido in Women Receiving Aromatase Inhibitors for Early-Stage Breast Cancer: A Randomized Clinical Trial.| | PubMed
- Association Between Use of a Scalp Cooling Device and Alopecia After Chemotherapy for Breast Cancer.| | PubMed
- Precision surgery and avoiding over-treatment.| | PubMed
- Breast Cancer Screening in the Precision Medicine Era: Risk-Based Screening in a Population-Based Trial.| | PubMed
- Ki67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance).| | PubMed
- Dedicated Breast Positron Emission Tomography for the Evaluation of Early Response to Neoadjuvant Chemotherapy in Breast Cancer.| | PubMed
- MR spectroscopy of breast cancer for assessing early treatment response: Results from the ACRIN 6657 MRS trial.| | PubMed
- Do Prolonged Prophylactic Antibiotics Reduce the Incidence of Surgical-Site Infections in Immediate Prosthetic Breast Reconstruction?| | PubMed
- Effect of MR Imaging Contrast Thresholds on Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer Subtypes: A Subgroup Analysis of the ACRIN 6657/I-SPY 1 TRIAL.| | PubMed
- Co-expression modules identified from published immune signatures reveal five distinct immune subtypes in breast cancer.| | PubMed
- Characterizing the immune microenvironment in high-risk ductal carcinoma in situ of the breast.| | PubMed
- Adaptive Randomization of Neratinib in Early Breast Cancer.| | PubMed
- PIPELINEs: Creating Comparable Clinical Knowledge Efficiently by Linking Trial Platforms.| | PubMed
- The I-SPY approach to drug development.| | PubMed
- Laura Esserman and Ian Thompson Discuss Strategies for Screening and Treatment of Early-Stage Cancers, and How Clinicians Can Learn From Each Other's Experiences.| | PubMed
- The Novel Application of Genomic Profiling Assays to Shorten Inactive Status for Potential Kidney Transplant Recipients With Breast Cancer.| | PubMed
- Adaptive Randomization of Neratinib in Early Breast Cancer.| | PubMed
- Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer.| | PubMed
- When Less Is Better, but Physicians Are Afraid Not to Intervene.| | PubMed
- Proteomic mapping of p53 immunogenicity in pancreatic, ovarian, and breast cancers.| | PubMed
- Outcomes Following Oncoplastic Reduction Mammoplasty: A Systematic Review.| | PubMed
- Population-based screening for cancer: hope and hype.| | PubMed
- When the Gold Standard Loses Its Luster, Perhaps It Is Time to Change Nomenclature.| | PubMed
- Treatment and Long-Term Risks for Patients With a Diagnosis of Ductal Carcinoma In Situ-Reply.| | PubMed
- Effect of Imaging Parameter Thresholds on MRI Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer Subtypes.| | PubMed
- A phase 1b study of the Akt-inhibitor MK-2206 in combination with weekly paclitaxel and trastuzumab in patients with advanced HER2-amplified solid tumor malignancies.| | PubMed
- Time for a randomised clinical trial evaluating breast conserving surgery compared to mastectomy in ipsilateral mutlifocal breast cancer (MFBC)?| | PubMed
- Detection of ductal carcinoma in situ and subsequent interval cancers.| | PubMed
- CLINICAL DECISIONS. Ductal Carcinoma In Situ.| | PubMed
- Less Is More: The Evolving Surgical Approach to Breast Cancer.| | PubMed
- Neoadjuvant as Future for Drug Development in Breast Cancer--Response.| | PubMed
- The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander-Implant Exchange in Prosthetic Breast Reconstruction.| | PubMed
- Tissue Expander Reconstruction After Total Skin-Sparing Mastectomy: Defining the Effects of Coverage Technique on Nipple/Areola Preservation.| | PubMed
- Sentinel Lymph Node Mapping in Post-Mastectomy Chest Wall Recurrences: Influence on Radiation Treatment Fields and Outcome.| | PubMed
- Neoadjuvant Chemotherapy for Breast Cancer: Functional Tumor Volume by MR Imaging Predicts Recurrence-free Survival-Results from the ACRIN 6657/CALGB 150007 I-SPY 1 TRIAL.| | PubMed
- Rethinking the Standard for Ductal Carcinoma In Situ Treatment.| | PubMed
- Negative Genetic Testing Does Not Deter Contralateral Prophylactic Mastectomy in Younger Patients with Greater Family Histories of Breast Cancer.| | PubMed
- Association of tamoxifen use and ovarian function in patients with invasive or pre-invasive breast cancer.| | PubMed
- Standardization of pathologic evaluation and reporting of postneoadjuvant specimens in clinical trials of breast cancer: recommendations from an international working group.| | PubMed
- How to use magnetic resonance imaging following neoadjuvant chemotherapy in locally advanced breast cancer.| | PubMed
- Expanding the Indications for Total Skin-Sparing Mastectomy: Is It Safe for Patients with Locally Advanced Disease?| | PubMed
- In Regard to Hepel and Wazer.| | PubMed
- Preventing Overdiagnosis and Overtreatment: Just the Next Step in the Evolution of Breast Cancer Care.| | PubMed
- Serial expression analysis of breast tumors during neoadjuvant chemotherapy reveals changes in cell cycle and immune pathways associated with recurrence and response.| | PubMed
- Tumor Involvement of the Nipple in Total Skin-Sparing Mastectomy: Strategies for Management.| | PubMed
- Coaching patients in the use of decision and communication aids: RE-AIM evaluation of a patient support program.| | PubMed
- Recommendations for standardized pathological characterization of residual disease for neoadjuvant clinical trials of breast cancer by the BIG-NABCG collaboration.| | PubMed
- Comparison of Mammographic Findings Following Oncoplastic Mammoplasty and Lumpectomy Without Reconstruction.| | PubMed
- Approaches to microvascular breast reconstruction after total skin-sparing mastectomy: a comparison of techniques.| | PubMed
- Rates of Reconstruction Failure in Patients Undergoing Immediate Reconstruction With Tissue Expanders and/or Implants and Postmastectomy Radiation Therapy.| | PubMed
- Pride, Prejudice, or Science: Attitudes Towards the Results of the TARGIT-A Trial of Targeted Intraoperative Radiation Therapy for Breast Cancer.| | PubMed
- The impact of breast mass on outcomes of total skin-sparing mastectomy and immediate tissue expander-based breast reconstruction.| | PubMed
- The Neoadjuvant Model Is Still the Future for Drug Development in Breast Cancer.| | PubMed
- Development, implementation, and initial evaluation of a foundational open interoperability standard for oncology treatment planning and summarization.| | PubMed
- Preoperative Breast Pain Predicts Persistent Breast Pain and Disability After Breast Cancer Surgery.| | PubMed
- Construction and analysis of the NCI-EDRN breast cancer reference set for circulating markers of disease.| | PubMed
- SIS.NET: a randomized controlled trial evaluating a web-based system for symptom management after treatment of breast cancer.| | PubMed
- Expression profiling of circulating tumor cells in metastatic breast cancer.| | PubMed
- Immediate implant-based breast reconstruction following total skin-sparing mastectomy: defining the risk of preoperative and postoperative radiation therapy for surgical outcomes.| | PubMed
- Aggregate cost of mammography screening in the United States.| | PubMed
- Randomized trial of drain antisepsis after mastectomy and immediate prosthetic breast reconstruction.| | PubMed
- Haste makes waste, but lack of urgency is opportunity lost.| | PubMed
- Impact of total skin-sparing mastectomy incision type on reconstructive complications following radiation therapy.| | PubMed
- Moving beyond the breast cancer screening debate.| | PubMed
- Total skin-sparing mastectomy and immediate breast reconstruction: an evolution of technique and assessment of outcomes.| | PubMed
- Immediate implant-based breast reconstruction following total skin-sparing mastectomy in women with a history of augmentation mammaplasty: assessing the safety profile.| | PubMed
- Imaging features of HER2 overexpression in breast cancer: a systematic review and meta-analysis.| | PubMed
- Addressing overdiagnosis and overtreatment in cancer: a prescription for change.| | PubMed
- Fifty years of age-based screening: time for a new risk-based screening approach.| | PubMed
- Local recurrence rates are low in high-risk neoadjuvant breast cancer in the I-SPY 1 Trial (CALGB 150007/150012; ACRIN 6657).| | PubMed
- Oncoplastic mammoplasty as a strategy for reducing reconstructive complications associated with postmastectomy radiation therapy.| | PubMed
- Patient-reported outcomes and satisfaction after total skin-sparing mastectomy and immediate expander-implant reconstruction.| | PubMed
- Accelerated approval for pertuzumab in the neoadjuvant setting: winds of change?| | PubMed
- Pretreatment vitamin D level and response to neoadjuvant chemotherapy in women with breast cancer on the I-SPY trial (CALGB 150007/150015/ACRIN6657).| | PubMed
- Setting a research agenda for ductal carcinoma in situ that meets the current need for change.| | PubMed
- Application of a decision analytic framework for adoption of clinical trial results: are the data regarding TARGIT-A IORT ready for prime time?| | PubMed
- Abstract 124: outcomes of total skin-sparing mastectomy and reconstruction in 924 breasts over 11 years.| | PubMed
- Making better doctors: a survey of premedical interns working as health coaches.| | PubMed
- Characteristics of individuals with breast cancer rearrangements in BRCA1 and BRCA2.| | PubMed
- Aggregate cost of mammography screening in the United States: comparison of current practice and advocated guidelines.| | PubMed
- Real-Time Measurement of Functional Tumor Volume by MRI to Assess Treatment Response in Breast Cancer Neoadjuvant Clinical Trials: Validation of the Aegis SER Software Platform.| | PubMed
- Mammographic screening detects low-risk tumor biology breast cancers.| | PubMed
- Development of a personalized decision aid for breast cancer risk reduction and management.| | PubMed
- Changing the terminology of cancer--reply.| | PubMed
- Optimized breast MRI functional tumor volume as a biomarker of recurrence-free survival following neoadjuvant chemotherapy.| | PubMed
- Evolving paradigm for imaging, diagnosis, and management of DCIS.| | PubMed
- Patient preferences regarding intraoperative versus external beam radiotherapy following breast-conserving surgery.| | PubMed
- Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial.| | PubMed
- Screening: biology dictates the fate of young women with breast cancer.| | PubMed
- The prognostic implications of macrophages expressing proliferating cell nuclear antigen in breast cancer depend on immune context.| | PubMed
- Impact of ductal carcinoma in situ terminology on patient treatment preferences.| | PubMed
- Overdiagnosis and overtreatment in cancer: an opportunity for improvement.| | PubMed
- Total skin-sparing mastectomy in BRCA mutation carriers.| | PubMed
- The Athena Breast Health Network: developing a rapid learning system in breast cancer prevention, screening, treatment, and care.| | PubMed
- Cost-effectiveness analysis of intraoperative radiation therapy for early-stage breast cancer.| | PubMed
- Clinically meaningful tumor reduction rates vary by prechemotherapy MRI phenotype and tumor subtype in the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).| | PubMed
- Feasibility of Performing Total Skin-Sparing Mastectomy in Patients With Prior Circumareolar Mastopexy or Reduction Mammoplasty Incisions.| | PubMed
- Reducing false-positive biopsies: a pilot study to reduce benign biopsy rates for BI-RADS 4A/B assessments through testing risk stratification and new thresholds for intervention.| | PubMed
- Recognising the benefits and harms of breast cancer screening: an opportunity to target improvement.| | PubMed
- Total skin-sparing mastectomy: a systematic review of oncologic outcomes and postoperative complications.| | PubMed
- Developing safety criteria for introducing new agents into neoadjuvant trials.| | PubMed
- Reply: The effects of acellular dermal matrix in expander-implant breast reconstruction after total skin-sparing mastectomy.| | PubMed
- An optimized five-gene multi-platform predictor of hormone receptor negative and triple negative breast cancer metastatic risk.| | PubMed
- Physician behaviors surrounding the implementation of decision and communication AIDS in a breast cancer clinic: a qualitative analysis of staff intern perceptions.| | PubMed
- Will early detection for breast cancer ever work?| | PubMed
- Adaptive trials in the neoadjuvant setting: a model to safely tailor care while accelerating drug development.| | PubMed
- Breast cancer follow-up and management after primary treatment: American Society of Clinical Oncology clinical practice guideline update.| | PubMed
- Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping.| | PubMed
- Lobular histology and response to neoadjuvant chemotherapy in invasive breast cancer.| | PubMed
- Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors.| | PubMed
- Increasing the time to expander-implant exchange after postmastectomy radiation therapy reduces expander-implant failure.| | PubMed
- Breast cancer screening: the questions answered.| | PubMed
- The impact of an electronic health questionnaire on symptom management and behavior reporting for breast cancer survivors.| | PubMed
- Adoption, acceptability, and accuracy of an online clinical trial matching website for breast cancer.| | PubMed
- Biology of breast cancer in Nigerian women: a pilot study.| | PubMed
- Whole-genome analysis informs breast cancer response to aromatase inhibition.| | PubMed
- A common language in neoadjuvant breast cancer clinical trials: proposals for standard definitions and endpoints.| | PubMed
- Evaluating the feasibility of extended partial mastectomy and immediate reduction mammoplasty reconstruction as an alternative to mastectomy.| | PubMed
- Locally advanced breast cancer: MR imaging for prediction of response to neoadjuvant chemotherapy--results from ACRIN 6657/I-SPY TRIAL.| | PubMed
- The effects of acellular dermal matrix in expander-implant breast reconstruction after total skin-sparing mastectomy: results of a prospective practice improvement study.| | PubMed
- Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: results from the I-SPY 1 TRIAL--CALGB 150007/150012, ACRIN 6657.| | PubMed
- Elevated levels of proliferating and recently migrated tumor-associated macrophages confer increased aggressiveness and worse outcomes in breast cancer.| | PubMed
- Breast cancer recurrence is dictated by high-risk biology, not choice of surgery.| | PubMed
- Outcomes after total skin-sparing mastectomy and immediate reconstruction in 657 breasts.| | PubMed
- MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition.| | PubMed
- Overdiagnosis and overtreatment of breast cancer.| | PubMed
- Targeting Molecular Aberrations in Breast Cancer: Is It about Time?| | PubMed
- Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).| | PubMed
- Accelerating identification and regulatory approval of investigational cancer drugs.| | PubMed
- Proposals for uniform collection of biospecimens from neoadjuvant breast cancer clinical trials: timing and specimen types.| | PubMed
- Impact of mammographic screening on the detection of good and poor prognosis breast cancers.| | PubMed
- Outcome of long term active surveillance for estrogen receptor-positive ductal carcinoma in situ.| | PubMed
- Leukocyte composition of human breast cancer.| | PubMed
- Locally advanced breast cancers are more likely to present as Interval Cancers: results from the I-SPY 1 TRIAL (CALGB 150007/150012, ACRIN 6657, InterSPORE Trial).| | PubMed
- Elevated PCNA+ tumor-associated macrophages in breast cancer are associated with early recurrence and non-Caucasian ethnicity.| | PubMed
- Biologic markers determine both the risk and the timing of recurrence in breast cancer.| | PubMed
- A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.| | PubMed
- Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based int| | PubMed
- Characterizing the impact of 25 years of DCIS treatment.| | PubMed
- The impact of preoperative magnetic resonance imaging on surgical treatment and outcomes for ductal carcinoma in situ.| | PubMed
- Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics.| | PubMed
- A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer.| | PubMed
- The Communication and Care Plan: a novel approach to patient-centered clinical information systems.| | PubMed
- Long-term prognostic role of functional limitations among women with breast cancer.| | PubMed
- Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome.| | PubMed
- Intraoperative frozen section analysis of sentinel lymph nodes in breast cancer patients: a meta-analysis and single-institution experience.| | PubMed
- Impact of chemotherapy on postoperative complications after mastectomy and immediate breast reconstruction.| | PubMed
- Lessons learned from genetic testing.| | PubMed
- Expanding the reach of decision and communication aids in a breast care center: a quality improvement study.| | PubMed
- Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial.| | PubMed
- Is radiation indicated in patients with ductal carcinoma in situ and close or positive mastectomy margins?| | PubMed
- Solving the overdiagnosis dilemma.| | PubMed
- Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer.| | PubMed
- Application of screening principles to the reconstructed breast.| | PubMed
- Rethinking screening for breast cancer and prostate cancer.| | PubMed
- Bacteriologic features of surgical site infections following breast surgery.| | PubMed
- Pathologic and biologic response to preoperative endocrine therapy in patients with ER-positive ductal carcinoma in situ.| | PubMed
- A comparison of RNA amplification techniques at sub-nanogram input concentration.| | PubMed
- I-SPY 2: an adaptive breast cancer trial design in the setting of neoadjuvant chemotherapy.| | PubMed
- Improved surgical outcomes for breast cancer patients receiving neoadjuvant aromatase inhibitor therapy: results from a multicenter phase II trial.| | PubMed
- Prognostic implications of positive nonsentinel lymph nodes removed during selective sentinel lymphadenectomy for breast cancer.| | PubMed
- Oncologist use of the Adjuvant! model for risk communication: a pilot study examining patient knowledge of 10-year prognosis.| | PubMed
- The UCSC Cancer Genomics Browser.| | PubMed
- Hypertension is an independent predictor of survival disparity between African-American and white breast cancer patients.| | PubMed
- Total skin-sparing mastectomy: complications and local recurrence rates in 2 cohorts of patients.| | PubMed
- When informed, all women do not prefer breast conservation.| | PubMed
- Sensitivity to input variability of the Adjuvant! Online breast cancer prognostic model.| | PubMed
- Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature.| | PubMed
- Converting evidence to practice: a guide for the clinical application of MRI for the screening and management of breast cancer.| | PubMed
- Is it necessary to harvest additional lymph nodes after resection of the most radioactive sentinel lymph node in breast cancer?| | PubMed
- Monitoring the implementation of Consultation Planning, Recording, and Summarizing in a breast care center.| | PubMed
- Invasive breast cancer: predicting disease recurrence by using high-spatial-resolution signal enhancement ratio imaging.| | PubMed
- Risk communication with patients with breast cancer: cautionary notes about printing Adjuvant! estimates.| | PubMed
- Estrogen receptor-negative breast cancer is less likely to arise among lipophilic statin users.| | PubMed
- Statement of the science concerning locoregional treatments after preoperative chemotherapy for breast cancer: a National Cancer Institute conference.| | PubMed
- Multiplexed cell signaling analysis of human breast cancer applications for personalized therapy.| | PubMed
- Training community resource center and clinic personnel to prompt patients in listing questions for doctors: follow-up interviews about barriers and facilitators to the implementation of consultation planning.| | PubMed
- Optimizing the total skin-sparing mastectomy.| | PubMed
- A role for biomarkers in the screening and diagnosis of breast cancer in younger women.| | PubMed
- Treatment with autologous antigen-presenting cells activated with the HER-2 based antigen Lapuleucel-T: results of a phase I study in immunologic and clinical activity in HER-2 overexpressing breast cancer.| | PubMed
- Fluorescence in situ hybridization of ductal lavage samples identifies malignant phenotypes from cytologically normal cells in women with breast cancer.| | PubMed
- Pilot trial of a computerized decision aid for breast cancer prevention.| | PubMed
- Ductal carcinoma in situ in BRCA mutation carriers.| | PubMed
- Analysis of molecular inversion probe performance for allele copy number determination.| | PubMed
- Genomic and transcriptional aberrations linked to breast cancer pathophysiologies.| | PubMed
- Type and duration of exogenous hormone use affects breast cancer histology.| | PubMed
- Biologic significance of false-positive magnetic resonance imaging enhancement in the setting of ductal carcinoma in situ.| | PubMed
- Magnetic resonance imaging captures the biology of ductal carcinoma in situ.| | PubMed
- Breast cancer growth prevention by statins.| | PubMed
- Evaluation of a visit preparation intervention implemented in two rural, underserved counties of Northern California.| | PubMed
- Challenge with mammary tumor cells expressing MHC class II and CD80 prevents the development of spontaneously arising tumors in MMTV-neu transgenic mice.| | PubMed
- Clinical trials are required to prove the chemopreventive worth of statins.| | PubMed
- A call for clinical trials: lipophilic statins may prove effective in treatment and prevention of particular breast cancer subtypes.| | PubMed
- Mammographic, sonographic, and pathologic characteristics of Burkitt's lymphoma in a patient referred for diagnostic mammography.| | PubMed
- Breast cancer risk assessment and prevention: a framework for shared decision-making consultations.| | PubMed
- Genetic/familial high-risk assessment: breast and ovarian.| | PubMed
- Statins: health-promoting agents show promise for breast cancer prevention.| | PubMed
- Tamoxifen may prevent both ER+ and ER- breast cancers and select for ER- carcinogenesis: an alternative hypothesis.| | PubMed
- Genetic testing in an ethnically diverse cohort of high-risk women: a comparative analysis of BRCA1 and BRCA2 mutations in American families of European and African ancestry.| | PubMed
- Primary tumor characteristics predict sentinel lymph node macrometastasis in breast cancer.| | PubMed
- The effect of sentinel node tumor burden on non-sentinel node status and recurrence rates in breast cancer.| | PubMed
- Ratio of positive to total number of sentinel nodes predicts nonsentinel node status in breast cancer patients.| | PubMed
- MRI measurements of breast tumor volume predict response to neoadjuvant chemotherapy and recurrence-free survival.| | PubMed
- Mapping molecular networks using proteomics: a vision for patient-tailored combination therapy.| | PubMed
- Immune dysfunction and micrometastases in women with breast cancer.| | PubMed
- Integration of imaging in the management of breast cancer.| | PubMed
- Development of a novel method for measuring in vivo breast epithelial cell proliferation in humans.| | PubMed
- Safety of immediate transverse rectus abdominis myocutaneous breast reconstruction for patients with locally advanced disease.| | PubMed
- Internal mammary sentinel lymph node mapping for invasive breast cancer: implications for staging and treatment.| | PubMed
- Recruitment, genetic counseling, and BRCA testing for underserved women at a public hospital.| | PubMed
- Accuracy of selective sentinel lymphadenectomy after neoadjuvant chemotherapy: effect of clinical node status at presentation.| | PubMed
- Evaluation of breast cancer risk assessment techniques: a cost-effectiveness analysis.| | PubMed
- Clonality of lobular carcinoma in situ and synchronous invasive lobular carcinoma.| | PubMed
- Applying the neoadjuvant paradigm to ductal carcinoma in situ.| | PubMed
- Neoadjuvant chemotherapy for primary breast cancer: lessons learned and opportunities to optimize therapy.| | PubMed
- Neoadjuvant hormonal therapy for ductal carcinoma in situ: trial design and preliminary results.| | PubMed
- An XML message broker framework for exchange and integration of microarray data.| | PubMed
- Racial differences in mammographic breast density.| | PubMed
- Cyclooxygenase-2 expression is related to nuclear grade in ductal carcinoma in situ and is increased in its normal adjacent epithelium.| | PubMed
- Magnetic resonance imaging in patients diagnosed with ductal carcinoma-in-situ: value in the diagnosis of residual disease, occult invasion, and multicentricity.| | PubMed
- MHC class II enhanceosome: how is the class II transactivator recruited to DNA-bound activators?| | PubMed
- Failure to harvest sentinel lymph nodes identified by preoperative lymphoscintigraphy in breast cancer patients.| | PubMed
- Efficacy of computerized infrared imaging analysis to evaluate mammographically suspicious lesions.| | PubMed
- Improving the quality of decision making in breast cancer: consultation planning template and consultation recording template.| | PubMed
- Accuracy of MR imaging for revealing residual breast cancer in patients who have undergone neoadjuvant chemotherapy.| | PubMed
- Axillary metastasis from a malignant mullerian mixed tumor.| | PubMed
- Major histocompatibility complex class II transcriptional platform: assembly of nuclear factor Y and regulatory factor X (RFX) on DNA requires RFX5 dimers.| | PubMed
- Pretest prediction of BRCA1 or BRCA2 mutation by risk counselors and the computer model BRCAPRO.| | PubMed
- Consultation planning to help breast cancer patients prepare for medical consultations: effect on communication and satisfaction for patients and physicians.| | PubMed
- Epithelial and fibroblast cell lines derived from a spontaneous mammary carcinoma in a MMTV/neu transgenic mouse.| | PubMed
- Magnetic resonance imaging for primary breast cancer management: current role and new applications.| | PubMed
- Skin-sparing mastectomy and immediate breast reconstruction: a prospective cohort study for the treatment of advanced stages of breast carcinoma.| | PubMed
- New approaches to the imaging, diagnosis, and biopsy of breast lesions.| | PubMed
- Improving the accuracy of mammography: volume and outcome relationships.| | PubMed
- Ductal lavage for detection of cellular atypia in women at high risk for breast cancer.| | PubMed
- Does timely assessment affect the anxiety associated with an abnormal mammogram result?| | PubMed
- MRI phenotype is associated with response to doxorubicin and cyclophosphamide neoadjuvant chemotherapy in stage III breast cancer.| | PubMed
- The impact of alternative practices on the cost and quality of mammographic screening in the United States.| | PubMed
- Ductal growth is impeded in mammary glands of C-neu transgenic mice.| | PubMed
- MR imaging of the breast in patients with positive margins after lumpectomy: influence of the time interval between lumpectomy and MR imaging.| | PubMed
- Integration of breast imaging into cancer management.| | PubMed
- Dynamic high-spatial-resolution MR imaging of suspicious breast lesions: diagnostic criteria and interobserver variability.| | PubMed
- Current national health insurance coverage policies for breast and ovarian cancer prophylactic surgery.| | PubMed
- Building bridges between physicians and patients: results of a pilot study examining new tools for collaborative decision making in breast cancer.| | PubMed
- Management of ductal carcinoma in situ.| | PubMed
- Biological therapies for breast carcinoma: concepts for improvement in survival.| | PubMed
- Prophylactic mastectomy in women with a high risk of breast cancer.| | PubMed
- Vaccination with the extracellular domain of p185neu prevents mammary tumor development in neu transgenic mice.| | PubMed
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- Is routine frozen section assessment feasible in the practice environment of the 1990s?| | PubMed
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- Ultrasound tissue characterization of breast biopsy specimens: expanded study.| | PubMed
- Barriers to care and treatment: the challenge of daily radiation therapy.| | PubMed
- Should we recommend screening mammography for women aged 40 to 49?| | PubMed
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- Trade-offs between survival and breast preservation for three initial treatments of ductal carcinoma-in-situ of the breast.| | PubMed
- Potentially ineffective care. A new outcome to assess the limits of critical care.| | PubMed
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- An epitope on the transferrin receptor preferentially exposed during tumor progression in human lymphoma is close to the ligand binding site.| | PubMed
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- Development of a new therapeutic approach to B cell malignancy. The induction of immunity by the host against cell surface receptor on the tumor.| | PubMed
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