University of California San Francisco

Bautista, Jhoanne
Jhoanne Bautista, MD, PhD

Graduate
General Surgery Residency Program, 2022

Address

513 Parnassus Avenue, MSB, #321A
San Francisco, CA 94143
United States

    Biography

    Jhoanne (Joey) Bautista MD PhD is a General Surgery Resident in the UCSF Department of Surgery. During her research years, Dr. Bautista was a Research Fellow in the UCSF Diabetes Center where she applied bioinformatics to the study of the development of tolerogenic antigen presenting cells in both the thymus and periphery.

    Education

    Education

    Barnard College (New York, NY) - BA Biochemistry 1999
    Massachusetts Institute of Technology (Cambridge, MA) - MS Inorganic Chemistry 2003
    Washington University in St. Louis School of Medicine (St. Louis, MO) - PhD Immunology 2014 
    Washington University in St. Louis School of Medicine (St. Louis, MO) - MD 2014

    Residencies

    University of California San Francisco Medical Center - General Surgery Intern - 2014-2015
    University of California San Francisco Medical Center - General Surgery Resident - 2015-present

    Fellowships

    Resident Research Fellow - Diabetes Center - 2017-2019

    Postdoctoral Training

    Postdoctoral Trainee/Fellow - Diabetes Center - 2017-Present

    Clinical Interests

    Abdominal Transplantation
    Surgical Management of Autoimmune Diseases

    Research Interests

    Thymic development
    Antigen presentation in auto/alloreactivity and tolerance
    Transplant immunology
    Bioinformatics

    Publications

    MOST RECENT PUBLICATIONS FROM A TOTAL OF 16
    1. Single-cell multiomics defines tolerogenic extrathymic Aire-expressing cells with unique homology to thymic epithelium.
      Jiaxi Wang, Caleb A Lareau, Jhoanne L Bautista, Im Hong Sun, Alexander R Gupta, James M Gardner| | UCSF Research Profile
    2. Single-cell multiomics defines tolerogenic extrathymic Aire-expressing populations with unique homology to thymic epithelium.
      Wang J, Lareau CA, Bautista JL, Gupta AR, Sandor K, Germino J, Yin Y, Arvedson MP, Reeder GC, Cramer NT, Xie F, Ntranos V, Satpathy AT, Anderson MS, Gardner JM| | PubMed
    3. Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla.
      Bautista JL, Cramer NT, Miller CN, Chavez J, Berrios DI, Byrnes LE, Germino J, Ntranos V, Sneddon JB, Burt TD, Gardner JM, Ye CJ, Anderson MS, Parent AV| | PubMed
    4. Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma.
      Moore PC, Cortez JT, Chamberlain CE, Alba D, Berger AC, Quandt Z, Chan A, Cheng MH, Bautista JL, Peng J, German MS, Anderson MS, Oakes SA| | PubMed
    5. Aire deficiency during early pregnancy leads to maternal T cell imbalance and embryo loss.
      Eva Mae Gillis-Buck, James M. Gardner, Jhoanne L. Bautista, Mark S. Anderson, Adrian Erlebacher, Tippi C. MacKenzie| | UCSF Research Profile
    6. Autoimmune regulator gene supports maternal-fetal immune tolerance during early pregnancy.
      Eva Mae Gillis-Buck, Jhoanne L. Bautista, Mark S. Anderson, Tippi C. MacKenzie| | UCSF Research Profile
    7. A broad range of self-reactivity drives thymic regulatory T cell selection to limit responses to self.
      Lee HM, Bautista JL, Scott-Browne J, Mohan JF, Hsieh CS| | PubMed
    8. Responsiveness to IL-2 characterizes a stable Foxp3+ subset in mice (148.16).
      Jhoanne Bautista, Susan Gilfillan, Marco Colonna, Chyi-Song Hsieh| | UCSF Research Profile
    9. Thymic and peripheral differentiation of regulatory T cells.
      Lee HM, Bautista JL, Hsieh CS| | PubMed
    10. Sliding set-points of immune responses for therapy of autoimmunity.
      Hsieh CS, Bautista JL| | PubMed
    11. Absence of P-selectin in recipients of allogeneic bone marrow transplantation ameliorates experimental graft-versus-host disease.
      Lu SX, Holland AM, Na IK, Terwey TH, Alpdogan O, Bautista JL, Smith OM, Suh D, King C, Kochman A, Hubbard VM, Rao UK, Yim N, Liu C, Laga AC, Murphy G, Jenq RR, Zakrzewski JL, Penack O, Dykstra L, Bampoe K, Perez L, Furie B, Furie B, van den Brink MR| | PubMed
    12. P-Selectin Regulates Leukocyte Trafficking And Experimental Graft-Versus-Host-Disease After Allogeneic Bone Marrow Transplantation.
      S.X. Lu, M.L. Palomba, I.-K. Na, T.H. Terwey, O. Alpdogan, J.L. Bautista, M. Smith, D. Suh, C.G. King, U.K. Rao, N. Yim, R.R. Jenq, J.L. Zakrzewski, A.M. Holland, O. Penack, L. Dykstra, K. Bampoe, M.R.M. van den Brink| | UCSF Research Profile
    13. Intraclonal competition limits the fate determination of regulatory T cells in the thymus.
      Bautista JL, Lio CW, Lathrop SK, Forbush K, Liang Y, Luo J, Rudensky AY, Hsieh CS| | PubMed
    14. SY-24 Thymic and peripheral regulatory T-cell development.
      Chyi-Song Hsieh, Chan Wang Lio, Stephanie K. Lathrop, Jhoanne Bautista, Hyang Mi Lee, Nicole San| | UCSF Research Profile
    15. An ITAM-signaling pathway controls cross-presentation of particulate but not soluble antigens in dendritic cells.
      Graham DB, Stephenson LM, Lam SK, Brim K, Lee HM, Bautista J, Gilfillan S, Akilesh S, Fujikawa K, Swat W| | PubMed
    16. Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCgamma2 signaling axis in mice.
      Graham DB, Robertson CM, Bautista J, Mascarenhas F, Diacovo MJ, Montgrain V, Lam SK, Cremasco V, Dunne WM, Faccio R, Coopersmith CM, Swat W| | PubMed